Alzheimer S Articles & Analysis
43 articles found
One notable study published in Nature Neuroscience (2021) demonstrated how CX3CL1-fractalkine signaling influences microglial activity in neurodegenerative diseases like Alzheimer’s. These findings suggest potential avenues for therapeutic intervention targeting neuroinflammation. ...
In the rapidly evolving field of pharmaceuticals, nanotechnology has emerged as a revolutionary force, transforming the landscape of drug delivery and formulation development. The integration of nanotechnology into pharmaceutical formulation offers unprecedented opportunities to enhance the efficacy, safety, and convenience of therapeutic interventions. This article explores the profound impact ...
Polyethylene glycol (PEG) derivatives have become pivotal in the pharmaceutical industry, revolutionizing drug delivery systems and enhancing the efficacy of various therapeutic agents. The unique properties of PEG derivatives, including their biocompatibility and ability to modify the solubility, stability, and bioavailability of drugs, make them indispensable in modern pharmacology. This ...
When it comes to the fascinating world of proteins, some names like collagen or hemoglobin might ring a bell. But what about tenascin-C, more commonly known as TNC protein? This often-overlooked molecule plays a vital, if subtle, role in how our cells talk to each other. Let's delve into the remarkable story of TNC protein and why it deserves more of the spotlight. What is TNC Protein? Before ...
Tau protein is a microtubule-associated protein, mainly present in nerve cells, and participates in the stabilization of microtubules. In certain neurodegenerative diseases, such as Alzheimer's disease (AD), Tau protein may undergo abnormal phosphorylation and aggregation, forming so-called Tau tangles or neurofibrillary tangles.Ubiquitination is a kind of post-translational modification of ...
Imagine a world where diseases like cancer, Alzheimer's, and Parkinson's could be diagnosed and treated at the molecular level, long before symptoms even appear. This is the promise of fluorescent biopolymers, a revolutionary new class of materials that could transform the field of biomedical research. What Are Fluorescent Biopolymers? At their core, biopolymers are simply long chains of ...
ByMatexcel
The field of medical science has long utilized disease models, which are systems simulating the progression and expression of a disease, to better understand various illnesses. These models facilitate the study of disease pathology, identifying underlying mechanisms, and developing potential treatments. In the context of respiratory diseases, numerous models have been developed, with a prominent ...
Nano-flow cytometry is a revolutionary technology that has the potential to transform early disease detection and diagnosis. Nano-flow cytometers are able to detect and analyze individual nanoparticles, including extracellular vesicles and viruses, with high sensitivity and accuracy. This makes them ideal for detecting diseases at their earliest stages, when they are most treatable. How does ...
The field of medical science has long utilized disease models, which are systems simulating the progression and expression of a disease, to better understand various illnesses. These models facilitate the study of disease pathology, identifying underlying mechanisms, and developing potential treatments. In the context of respiratory diseases, numerous models have been developed, with a prominent ...
In the realm of modern medicine, the quest for new and effective drugs to combat various diseases is a continuous journey. Drug discovery, the process of identifying compounds that can potentially treat diseases, has seen a significant transformation in recent years, thanks to advancements in computational biology and artificial intelligence (AI). In this article, we will delve into the ...
Introduction: Ox bile extract powder, derived from ox bile, is a natural product with a wide range of applications. It contains essential components such as bile acids, cholesterol, bilirubin, and fatty acids. Through meticulous preparation processes, it is transformed into a powdered form, enhancing its stability and convenience. Ox bile extract powder exhibits diverse applications in the fields ...
Previously, it was thought that glial cells, which support neuronal activity, metabolize most of the glucose in the brain. However, by using induced pluripotent stem cells, the researchers found that neurons were able to take up glucose and process it into smaller metabolites. In mice, normal function of neurons depends on glycolysis. The findings could help develop new treatments for ...
Targeted protein degradation (TPD) is a promising strategy in the field of drug discovery. In recent years, targeted protein degradation (TPD) technology has developed rapidly, especially proteolysis targeting chimera (PROTAC), which is the most representative technology of TPD strategy. TPD drugs are one of the hot spots of new drug development in recent years, especially in the field of ...
As we all know, proteins play important roles in human bodies since all physiologic events are related to the structural or mechanical functions of certain proteins. Studying the synthesis process of proteins is a way to study the etiology, pathophysiology, diagnosis, and treatment of certain diseases. The human genome contains approximately 3 billion base pairs of DNA. Among them, only about 30 ...
To understand the significance of the SpinTech MRI STAGE software platform, it helps to begin by asking a question: Given that MRI is an incredibly powerful diagnostic tool for neurological diseases like Alzheimer’s, dementia, Parkinson’s and multiple sclerosis (MS), why have radiologists and neurologists had to choose between ...
People living with frontotemporal dementia, or FTD, are commonly misdiagnosed with psychiatric disorders or Alzheimer’s disease and other causes of dementia, such as Parkinson’s disease and vascular dementia. While frontotemporal dementia and Alzheimer’s disease can both cause dementia, there ...
, this type of research helps medical researchers understand people’s health and how we can make treatments better for everyone. But health research isn’t possible without the contributions of research participants. ...
Today marks a historic day for all the scientists and researchers who have dedicated their lives to advancing our understanding of Alzheimer’s Disease over the last 20 years. For the more than 6 million individuals living with Alzheimer’s disease in the US, their families, and their caretakers, our team at Altoida ...
The PEMF technology has been studied by NASA in a four-year, $3.5 million study, with very positive ...
Alzheimer's disease (AD) is a progressive, irreversible neurodegenerative disease clinically manifested by cognitive impairment, behavioral abnormalities, and social deficits. It is predicted that by 2050, the number of people 65 and older with dementia in the United States could reach 13.8 million. In China, more than 15.07 million elderly people aged 60 or over suffer from dementia, of which ...