Antiviral Drug Articles & Analysis
15 articles found
For example, the incorporation of phosphorus-containing moieties can enhance the pharmacokinetic properties of drugs, improving their efficacy and bioavailability. Applications in Drug Development In the pharmaceutical industry, phosphorus compounds are particularly renowned for their applications as intermediates in drug synthesis. One notable ...
The COVID-19 pandemic has illuminated the critical need for innovative strategies in antiviral research, and scientists worldwide are embarking on groundbreaking projects to develop more effective therapies, vaccines, and preventive measures against a myriad of viral pathogens The Rise of Next-Generation Antivirals One of the most promising frontiers in ...
Applications of Glycan Arrays Glycan arrays have found numerous applications in various fields of research, including glycobiology, immunology, and drug discovery. Here are some key areas where glycan arrays have made significant contributions: Glycan-Protein Interactions: Glycan arrays allow researchers to study the specific interactions between glycans and proteins. ...
The coronavirus disease 2019 (COVID-19) pandemic has clearly demonstrated the need for broad-spectrum antiviral drugs that are effective in treating more than just one specific virus variant, virus species, or phylum. One strategy to develop long-lasting broad-spectrum antiviral drugs includes targeting host cell proteins that ...
One of the significant applications of protein-DNA docking is in drug discovery. By using molecular docking, researchers can identify small molecules that can bind to specific regions of DNA or protein-DNA complexes, which can lead to the development of new drugs. This approach has led to the development of several successful drugs, including ...
A new structural target for drug development against COVID-19 has been unveiled today by Sibylla Biotech in collaboration with the Italian National Institute of Nuclear Physics (INFN), the University of Trento and University of Perugia.The breakthrough drug discovery strategy pioneered by Sibylla in this study would not only promise to reduce the risk of ...
Liposomes vary in size, composition and charge and can be used as carriers for a wide range of drug molecules, such as chemotherapeutic agents, antimicrobial and antiviral drugs, antiparasitic drugs, genetic material, vaccines, therapeutic proteins, and anti-inflammatory agents. ...
Rational Vaccines noted that many antiviral drugs developed for herpes, which has been on the market since the 1970s, can reduce the severity and frequency of symptoms but cannot cure the infection. ...
The pharmaceutical industry has a notoriously slow business model, where a typical drug discovery program can take many years to successfully progress to a ready-to-prescribe drug. ...
Ensitrelvir also demonstrated antiviral effectiveness against SARS-CoV-2 variants of concern (VOCs), such as the highly pathogenic Delta variant and the newly discovered Omicron variant. Overall, these findings show that Ensitrelvir, which is an antiviral drug that is currently being tested in Phase II/III clinical trials, has impressive ...
His laboratory also studies the interaction of antibodies and viruses, providing clues for the design of antiviral drugs and vaccines for these two virus families. The researchers explain that Nipah virus and Hendra virus enter cells by binding and fusing glycoproteins that work together. ...
After therapy and withdrawal of antiviral drugs, HIVs were not identified in the patient's body for more than 14 months, indicating that the virus was in complete remission, according to academics. ...
The SOLIDARITY trial will seek to repurpose currently available drugs, evaluating the experimental antiviral remdesivir, the malaria drugs chloroquine and hydroxychloroquine, a combination of the HIV drugs lopinavir and ritonavir, and lopinavir—ritonavir plus interferon beta. ...
The only groups showing a decrease are the antivirals and drugs for addiction treatments as well as ethinylestradiol, an active compound in contraceptives.Keywords: ageing, population, prescribed pharmaceuticals, surface water, water ...
Prevention and management of viral disease heavily relies upon vaccines and antiviral medications (49). Both vaccines and antiviral medications are only 60% effective (39, 49). Additionally, to date there are no vaccines or antiviral drugs for most common enteric and respiratory viruses with the exception of influenza virus and ...