bioinformatics system Articles
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CD Genomics Perspective: Bioinformatic Analysis for HLA Genotyping
Introduction to HLA Human leukocyte antigen (HLA) is a 3.6 Mb segment on the short arm of chromosome 6 that contains over 200 genes. It is also known as the major histocompatibility complex (MHC), and it is the most polymorphic region in the human genome, involving diverse immune reactions. HLA is divided into HLA-class I (corresponding to MHC class I) and HLA-class II (corresponding to MHC class ...
By CD Genomics
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Drug Discovery: Unraveling the Mysteries of Therapeutic Agents
In the vast and ever-evolving field of medicine, the discovery of new drugs has been a critical pursuit, offering hope and relief to countless individuals suffering from various ailments. The process of drug discovery is a complex and multifaceted endeavor, involving the integration of diverse scientific disciplines, including biology, chemistry, and computational science. At the heart of this ...
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Project - VIBE Education Edition
Project Summary 1. Project Design Throughout the project, INCOGEN collaborated closely with a team of professionals from the College of William & Mary (W&M) and other institutions to develop an effective plan for assessment and design of the educational software and its introduction into the classroom. This team was comprised of bioinformatics educators from the Departments of Biology, ...
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Complexity metrics for ontology based information
An ontology defines technical terms and shows interrelationships between terms for particular application areas. XML-based standards such as OWL and DAML provide mechanisms to produce XML based ontologies. Ontologies are used in service matching and dynamic web service composition, and are heavily used in bioinformatics and genomics to characterise the structure of living things. Our research ...
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Mutation-directed Neo-protein-protein Interactions in Cancer
Genetic mutations in cells are an important cause of cancer development, progression, and drug resistance. How to quickly and accurately translate massive tumor genomic information into safe and effective cancer targeted therapies in clinical practice is a scientific frontier today. At present, a large number of scientific studies have focused on how oncogenic mutations regulate the activity of ...
By Profacgen
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