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Biomaterials Articles & Analysis
67 articles found
Idiopathic pulmonary fibrosis (IPF) is a devasting lung disease characterized by progressive scarring of lung tissue. As fibrosis develops, patients experience worsening shortness of breath, reduced lung capacity and ultimately respiratory failure. Current therapies for IPF rely on oral administration of pirfenidone and nintedanib, two FDA-approved drugs that slow disease progression. While ...
Regenerative Medicine A 2024 pilot study published in MDPI’s International Journal of Molecular Sciences showed that combining chitosan biomaterials with autologous stem cells led to near-complete healing of a chronic heel ulcer with osteomyelitis, illustrating chitosan’s promise in advanced regenerative therapies (MDPI IJMS). Conclusion Chitosan is a ...
ByMatexcel
In surgical tissue recovery, focus is on controlling infection, managing inflammation, and ensuring wound closure. Beneath the surface—anatomically and biologically— the extracellular matrix (ECM) is undergoing remodeling ensure long-term tissue integrity. The ECM is a dynamic, biologically active network that orchestrates the entire process of tissue repair, remodeling, and ...
Encapsulating anticancer drugs within its lipid bilayer improves drug accumulation in target tissues while reducing toxicity to healthy cells.Immunomodulatory TherapyFunctionalized DSPE-PEG-Mannose nanoparticles can modulate immune responses by interacting with mannose receptors on immune cells, contributing to novel treatments for immune-related disorders.Cell Recognition and SeparationBy ...
The continuous advancement of biomaterials has led to the development of various copolymers, among which Poly(lactic-co-glycolic acid) (PLGA) and Polyethylene Glycol (PEG) copolymers have garnered significant attention. ...
For example, bioengineers are investigating how to incorporate TNC protein into biomaterials to promote healing. Its ability to influence the immune system also makes it a potential player in autoimmune disease treatment. ...
Accurate determination of its concentration is crucial for multiple fields such as biomaterial research, food industry, and pharmaceutical research.Liquid Chromatography (LC) is an efficient and precise analytical technique for collagen concentration measurement, especially High-Performance Liquid Chromatography (HPLC) and Ultra-High Performance Liquid Chromatography (UHPLC) ...
Biomedical ResearchIn tissue engineering and regenerative medicine, understanding the molecular weight of collagen helps design suitable biomaterials.2. Drug DevelopmentInformation on the molecular weight of collagen is crucial for developing strategies that use collagen as a drug delivery carrier.3. ...
Presently, some of the popular areas of dendrimer engineering are drug delivery (by encapsulating drugs in their internal cavities and targeting them to specific tissues or cells), imaging (e.g. MRI and PET), biomaterials (e.g. scaffolds for cell growth), gene delivery (as vectors) and sensors (as they can bind to specific molecules). ...
The field of biomaterials is undergoing a transformative shift, driven by the integration of artificial intelligence (AI) technologies. ...
By creating biopolymers that bind to the toxic protein aggregates thought to cause these diseases, scientists hope to understand how and why these diseases develop, and potentially even halt their progression in its tracks. Smart Biomaterials for Regenerative Medicine Fluorescent biopolymers could also revolutionize the field of regenerative medicine. By designing biopolymers ...
ByMatexcel
From the development of eco-friendly detergents and leather processing agents to the creation of advanced biomaterials and biomedical implants, the versatility of this enzyme knows no bounds. ...
In addition, carboxylic acid PEGs can be used to construct imaging probes with specific biological activities, such as pH-responsive probes, temperature-sensitive probes, etc., for disease diagnosis and treatment monitoring. Biomaterials PEGs and their carboxylic acid derivatives also play an important role in biomaterials. ...
Advantages of Copper-Free Click Chemistry l Biocompatibility: Copper-free click chemistry is inherently more biocompatible than traditional copper-catalyzed click reactions, making it suitable for use in biological systems and live cell imaging without causing cytotoxicity. l Selectivity: Copper-free click reactions offer high selectivity, allowing for specific conjugation between biomolecules ...
Materials Science: Protein engineering is being used to design novel biomaterials with tailored properties for tissue engineering, drug delivery, and other applications. ...
In summary, the introduction of the fifth lipid greatly influences the bio-distribution of LNPs in major organs, and 50% cationic SORT lipid, 30% anionic SORT lipid, and 20% ionizable cationic SORT lipid promote the distribution of LNPs in the lung, spleen, and liver, respectively. 3) Bone targeting LNP: In recent years, there has been an increasing incidence of skeletal diseases and ...
Applications of Marine Polysaccharides With their unique chemical structure and properties, marine polysaccharides have found utility in sectors such as pharmaceuticals, food, cosmetics, agriculture, and biomaterials. l Pharmaceutical Marine polysaccharides have emerged as valuable resources in the field of pharmaceuticals due to their biocompatibility, low toxicity, and diverse ...
Hydrogels are a class of widely studied and applied biomaterials. Hydrogels have been widely studied as cell scaffolds and drug delivery vehicles because their chemical and physical properties are very close to the natural environment of cells. ...
Although it has been invented for more than 70 years, it is still an important biomaterial. The second category is covalently cross-linked hydrophilic polymers, mainly represented by polyvinyl alcohol (PVA) and polyethylene glycol (PEG), mainly It is used in tissue engineering. ...
One of the most important components for successful 3D printing is the ‘bioink’, the cell-laden biomaterial used to create the printed structure. Hydrogels are favoured bioinks used in extrusion-based bioprinting. ...