Clinical Outcome Assessment Articles & Analysis: Older
16 articles found
The scientific realm of biomedicine has witnessed extraordinary evolution in recent years, particularly in the spheres of cell and gene therapies. These therapies have radically revamped disease treatment modalities, transcending traditional approaches to become some of the most groundbreaking advancements in modern healthcare. This article aims to engage in an incisive analysis of cell and gene ...
Discover how matched tumor-normal sequencing can help clinical researchers detect the somatic origin of variants with certainty. In the era of precision oncology, it has become increasingly common for patients diagnosed with cancer to undergo tumor sequencing. Identifying the mutations that make up a tumor’s genomic landscape can help guide selection of targeted therapies and inform ...
Like any healthcare investment, consideration needs to be given when deciding which fractional exhaled nitric oxide (FeNO) device might best suit the clinical area in which it will be used. So, what would be sensible to consider when including FeNO devices for implementation into the respiratory pathway? And how does the NObreath® measure up? External approval is an important factor in ...
The scientific realm of biomedicine has witnessed extraordinary evolution in recent years, particularly in the spheres of cell and gene therapies. These therapies have radically revamped disease treatment modalities, transcending traditional approaches to become some of the most groundbreaking advancements in modern healthcare. This article aims to engage in an incisive analysis of cell and gene ...
The diagnostic approach is the same between both guidelines. The combination of clinical assessment, followed by natriuretic peptide measurement, echocardiographic indices of diastolic function, staging, and treatment initiation are all proposed in the diagnostic evaluation of patients with suspected HFpEF. The clinical composite score H2FPEF ...
With the rising demand for improving patient safety in clinical trials, the adoption of patient-centric solutions is considered the best route to enhance data accuracy and experience automated workflows. ...
ByClinion
Background Several pioneering studies have provided evidence for the introduction of universal pulse oximetry screening for critical congenital heart disease. I lowever, whether the benefits of screening reported in studies from high-income countries would translate with similar success to low-income countries is unknown. We assessed the feasibility and reliability of pulse oximetry plus clinical ...
BACKGROUND: Recent studies have shown that patient-triggered cardiac event recorders (CER) have an increased diagnostic yield and are more cost effective than conventional 24-h-Holter electrocardiograms (ECGs) for the evaluation of sporadic, potentially arrhythmia-related symptoms. HYPOTHESIS: The aim of this study was to determine the diagnostic yield of a patient-triggered CER combined with ...
ByNovacor
When promising drug candidates are identified for further investigation in clinical trials, sponsor companies are usually optimistic about outcomes. ...
Imagine you’ve just been diagnosed with cancer and you’re enrolled in a clinical trial for a promising new drug. You notice that after chemotherapy you struggle with occasional fatigue. ...
ByAiCure
The DASCOR Disc Arthroplasty Device seemed to perform well clinically but was discontinued in 2009. While there are no commercially available NRDs today, the potential advantages of using such devices have prompted a renewed interest in further developing the technology and assessing long-term outcomes for the DASCOR device. Methods A ...
It can be difficult to quantify change in an individual’s symptoms using standardized measurement tools, and points to the value of Patient—Centered Outcome Measures. As a relatively new concept, Patient—Centered Outcome Measures (PCOM) aims to place patients, their families and carers at the heart of the decision making that concerns their ...
We continue to assess the outcomes of T-Pin cases in the orthopaedic surgery community. We are seeking qualified surgeons to collect outcome data for patients whose fractures have been treated with the T-Pin System. Subjetive and objective assessment of factors such as patient selection factors, intraoperative observations and ...
Background and Purpose— A reliable measure of movement repetitions is required to assist in determining the optimal dose for maximizing upper limb recovery after stroke. This study investigated the ability of a new wearable device to capture reach-to-grasp repetitions in individuals with stroke. Methods— Eight individuals with stroke wore an instrumented wrist bracelet while ...
Clinic appointment cancellation and 'no–shows' by patients can disturb day–to–day scheduling and lead to inefficient resource allocation and lost revenue. This paper presents an approach for dynamic process modelling and analysis of patients' no–show rates in conjunction with the overbooking strategy. To this end, a dynamic discrete event simulation model of a clinic ...
Abstract: Clinic appointment cancellation and 'no-shows' by patients can disturb day-to-day scheduling and lead to inefficient resource allocation and lost revenue. This paper presents an approach for dynamic process modelling and analysis of patients' no-show rates in conjunction with the overbooking strategy. To this end, a dynamic discrete event simulation model of a clinic operation is ...