Clinical Sample Articles & Analysis
23 articles found
It is also used in ELISA platforms to quantify ELANE levels in clinical samples—useful for monitoring inflammation in pulmonary and systemic diseases. ...
Our kinetic analyses indicate that while traditional reaction buffers containing 10mM Mg²⁺ are sufficient for plasmid templates, complex genomic DNA samples benefit from supplementation with 0.5-1.0mM Mn²⁺, which enhances the enzyme's processivity on supercoiled substrates. ...
Our kinetic analyses indicate that while traditional reaction buffers containing 10mM Mg²⁺ are sufficient for plasmid templates, complex genomic DNA samples benefit from supplementation with 0.5-1.0mM Mn²⁺, which enhances the enzyme's processivity on supercoiled substrates. ...
For research and development (R&D) stages, customized dispensing equipment is available to avoid sample destruction and reduce development costs significantly. Product Types for Small Batch Production Various types of microspheres can be produced in small batches, catering to different pharmaceutical needs. ...
The remote blood collection technology needed to be easy for subjects to use, quick to deploy, and produce a stable clinical-grade sample. Further, overall user experience needed to be positive in order to encourage completion of the multiple blood collection timepoints required. “The nature of the studies we are performing—which involve multiple ...
By analyzing gene expression patterns in patient samples, scRNA-seq can identify molecular signatures associated with drug response or disease progression. ...
These models facilitate the study of disease progression, testing of drug candidates, and gaining insights into drug mechanisms of action. During the clinical development phase, scRNA-seq informs decision-making in several ways. ...
With the ability to rapidly produce large volumes of sequencing data, next-generation sequencing (NGS) enables researchers to obtain whole genome or targeted regions of samples. Targeted region sequencing is preferred by researchers and clinical doctors who focus on human diseases, which is based on the fact that genomics and epigenomics have identified a number ...
Challenge Calculating the appropriate sample size for a first of its kind stage-II colon cancer trial As Chairman of the Department of Biostatistics, Professor Satoshi Teramukai leads a variety of investigator-initiated clinical trials at the Kyoto Prefectural University of Medicine. With over 35 years experience, hundreds of published papers and thousands of ...
ByStatsol
Metagenomics presents a powerful tool to study prokaryotes and viruses in the environment via the analysis of their DNA obtained directly from environmental samples. This technology considers the DNA of microbes in a population as a whole. ...
FL), a new infrared non-contact forehead thermometer has been developed for clinical professional use. Our objective was to evaluate the clinical accuracy and repeatability of the Caregiver as compared to measurements obtained with an oral electronic thermometer in a family clinic and an out-patient pediatric clinic. ...
Herein, we provide an overview of the currently popular protein quantification technologies and their application in clinical research. Introduction of HPLC-MS/MS-based Proteomics Technology The development of high-performance liquid chromatography tandem mass spectrometry (HPLC-MS/MS) based proteomics technology mainly depends on the liquid chromatography-mass spectrometry ...
Metagenomics presents a powerful tool to study prokaryotes and viruses in the environment via the analysis of their DNA obtained directly from environmental samples. This technology considers the DNA of microbes in a population as a whole. ...
The Holiday season often brings mixed feelings for many. While it can be a time of relaxation with friends and family for some, for others, preparing for this time means ensuring business continuity despite a typical slow down. This can be a source of undue stress if it is not suitably planned for. ...
We generated a prediction model using 153 samples, with validation using an additional 58 clinical outcome-blinded samples. Gene expression profiles were generated using formalin-fixed, paraffin-embedded tissue samples and microarrays. Data analysis was performed using a supervised clustering method. The prediction model ...
This pathway is essential for the proliferation and survival of PDAC cells, so a deep understanding of the regulatory mechanism of this pathway is helpful to provide new ideas and targets for the clinical treatment of PDAC. O-GlcNAc glycosylation is a post-translational modification in which N-acetylglucosamine is covalently linked to the serine (Ser) or threonine (Thr) ...
An optimised biomedical cold storage environment, especially when equipped with Ultra-Low Freezers, can reliably store even the most thermosensitive biological samples for research purposes. In recent years, several beneficial cell samples and microbial strains have been discovered, engineered, and studied. ...
Short, single-stranded DNA or RNA oligonucleotide probes specific to the target regions are added to the mix and allowed to bind to the DNA sample after this, the unbound fragments are washed out from the sample. ...
This method has been widely used for the rapid diagnosis of bacteria in clinical, environmental, and industrial samples. Rapid pathogen identification aids in providing clinical diagnosis and selecting appropriate antibiotic treatment. It is also used in routine identification of bacteria in clinical laboratories to retrieve ...
In a recent paper authored by Wanyuan Ao et al., published in Journal of Clinical Microbiology (doi.org/10 .1128/JCM.00982-17), UCT’s polymer amine-functional T-structure polydimethylsiloxane ([TSPS] was used in the manufacturing process to coat crystalline silicon wafers in which curing took place at 150°C for 24 hours. ...