Refine by
Clinical Significance Articles & Analysis
24 articles found
Circulating Tumor Cells, or CTCs, are cancer cells that have shed from the primary tumor and enter the bloodstream, where they can travel and potentially lead to metastasis. These cells are of significant interest in oncology due to their potential to provide vital information about the tumor’s characteristics and behavior. ...
Research[16] has confirmed that the extracellular adenosine produced by CD73 on tumor cells plays a significant role in immune evasion, facilitating tumor growth and metastasis. ...
While predominantly found on the surface of B cells, CD19 is rarely expressed on other immune cells. Its significance lies in its involvement in B cell development and activation, making it a valuable target for research and clinical applications. ...
X-ZELL is collaborating with Singapore General Hospital (SGH) and the National University Hospital Singapore (NUH) to explore how X-ZELL single-cell diagnostics may aid in the early detection of clinically significant prostate cancer in whole blood. The prospectively blinded, 400-patient multi-centre study officially commenced in 2020 and will lay the foundation ...
Xu Kexin from Peking University People's Hospital whose team has been using M5 for about one year, we understand better its clinical significance. What has been your experience so far with M5? ...
The ClarityDX Prostate® test uses a proprietary machine-learning algorithm that combines data from biological and clinical biomarkers to generate a risk score for clinically significant prostate cancer, defined as Gleason grade group 2 or higher, on prostate biopsy. ...
Real-world data shows that at a 94% sensitivity level for prostate cancer ClarityDX Prostate® is 147% more specific than the PSA test for predicting clinically significant prostate cancer. Using ClarityDX Prostate® as a reflex test vs. ...
Clinical study launched in June 2022 with patient recruitment in Alberta with plans to expand to further sites across North America. ...
Researchers at the Palo Alto Veterans Affairs Health Care System showed that 89% of patients with PTSD had a clinically significant reduction in PTSD symptoms after the 28-day Freespira treatment. ...
BACKGROUND Non-invasive techniques like urinary biomarkers and multiparametric Magnetic Resonance Imaging (mpMRI) show great promise for the detection of clinically significant prostate cancer (PCa), leading to a reduction of over-diagnosis and over-treatment. ...
Organizations Martini-Klinik Prostate Cancer Center and Department of Urology, University Hospital Hamburg-Eppendorf, Hamburg, Germany, MDxHealth, B.V., Nijmegen, Netherlands, MDxHealth, Inc., Irvine, CA, Mathematical Modeling, Statistics and Bioinformatics, Ghent University, Ghent, Belgium, Martini-Klinik Prostate Cancer Center, University Hospital Hamburg-Eppendorf, Hamburg, Germany Abstract ...
There were no serious side effects in the inhalation group 28 days after booster vaccination, and there were no clinically significant lung function abnormalities in the different dose inhalation groups. ...
Study Results In an oral abstract of the Steripath Gen2 Initial Specimen Diversion Device® (ISDD) study results presented to PACCARB 2021, the Presidential Advisory Council on Combating Antibiotic-Resistant Bacterial titled “Getting to Zero: Eliminating Blood Culture Contamination with the ISDD,” Tompkins reported zero blood culture contamination events and near-zero ...
Many diagnosed at this stage will likely be disease free after 5 years, with an average 15 year survival rate of 95%.8 A missed diagnosis could be early stage cancer that may not be identified until later, potentially affecting chances of survival.2, 3 Surgical Backlog As hospitals and clinics are gradually permitted to perform more non-emergent surgeries, cancer diagnosis ...
Basically, it boils down to three key points: Transperineal virtually eliminates the risk of sepsis and the need for prophylactics, which has major savings for both clinics and patients. How major? If all urologists in the United States switched to transperineal, the potential savings on admissions for post transrectal biopsy sepsis would amount to between $341,676,800 and ...
As a kind of enzymes for diagnostic use. Serum amylase (AMS) is the main type of amylase in serum. It belongs to glycoside chain hydrolase, which is mainly derived from the pancreas. In addition, there are also a small amount of secretion in the proximal duodenum, lung, uterus, and breast during lactation. Amylase plays an important role in the digestion of polysaccharide compounds in food. The ...
Summary Nanostics' clinical validation study for ClarityDX Prostate, a liquid biopsy test for the early diagnosis of clinically significant prostate cancer, re-opens recruitment after lifting of COVID-19 research restrictions A top-ranked research institute in the Northeast US will now partner with Nanostics' by recruiting patients for the ...
Summary This study is designed to determine the accuracy of the blood test ClarityDX Prostate to predict the results of prostate biopsies in men who have PSA (Prostate Specific Antigen) greater than 3 and no higher than 10 ...
It was the first transcatheter mitral valve intervention therapy approved to treat select heart failure patients with clinically significant FMR. The Mitraclip system initially was indicated to reduce mitral regurgitation in certain patients whose significant mitral regurgitation and heart failure symptoms result from abnormalities of the mitral ...
There was no statistically significant improvement for the left knee’s range of motion or right ankle inversion. Forty percent of patients experienced clinically significant improvements in balance. Participants also saw a decrease in their scores on the MS Impact Scale-29 (a measure of how much the disease affects their lives) by a mean ...