Corneal Articles & Analysis
20 articles found
Human corneal epithelial cells play a vital role in maintaining the health and function of the cornea, the transparent front part of the eye. ...
HCEC-12 is a well-established human corneal epithelial cell line derived from human corneal tissue. It plays a crucial role in ocular research, particularly for studies related to corneal physiology, wound healing, and the pathogenesis of various ocular diseases. ...
Collagen films and tubes The isotropic collagen films prepared by evaporation have been widely used in the biomedicine of corneal repair due to its transparent nature and low demand for tissue mechanics. ...
Microspheres are small spherical entities formed by dispersing or adsorbing drugs in a polymer matrix. The particle size is typically between 1 μm and 250 μm, and the largest can reach more than 800 μm. Microsphere technology is at the intersection of cutting-edge disciplines such as materials science, polymer technology, medical technology, and microelectronics. Once injected into the ...
RVx201 Herpes Vaccine Description 2022 RVx201 is a first-in-human herpes simplex virus type 2 (HSV-2) live-attenuated therapeutic vaccine modified to be interferon sensitive that destroys the ability of the virus to inhibit immune responses. Produced by Rational Vaccines, Inc., the technology is based on the pioneering research of the late Dr. William Halford, who dedicated over 25 years to ...
Glycosaminoglycan (GAG) is a general term for the glycan part of proteoglycan macromolecules. Glycosaminoglycans are large linear polysaccharides composed of repeating disaccharide units, and their main configuration contains amino sugars and uronic acids (glucuronic acid and/or iduronic acid). Glycosaminoglycans can be divided into chondroitin sulfate, dermatan sulfate, keratan sulfate, ...
Abstract Purpose This case report demonstrates the effectiveness of a combined unique soft contact lens design and hypertonic saline at reducing corneal edema symptoms. In addition, this case shows that using tomographic data is invaluable for detecting and monitoring of these presentations. ...
Collagen is a family of proteins. At least 30 kinds of genes encoding collagen chains have been found, which can form more than 16 kinds of collagen molecules. According to its structure, it can be divided into fibrous collagen, basement membrane collagen, microfibrillar collagen, anchored collagen, hexagonal reticular collagen, non-fibrous collagen, transmembrane collagen, etc. According to ...
The primary endpoint of the trial measures the change from baseline in corneal fluorescein staining with a key secondary endpoint evaluating eye dryness symptoms using the visual analog scale (VAS). ...
Investigation of gene expression shifts in keratoconus patients' corneal epithelial tissue, for example, has revealed the cause of this progressive corneal degeneration. ...
Similar to a DMEK approach, it is implanted into the anterior chamber, carefully positioned on the posterior stroma, and secured using an air–gas mixture. Two patients with chronic corneal edema resulting from endothelial decompensation underwent implantation of the new artificial lamella. Results: In patient 1, the central corneal thickness (CCT) ...
To compare the safety and efficacy of the Therapeutic Hyper-CL™ lens versus a standard bandage contact lens (PureVision B&L) for chronic corneal edema. Methods. Prospective, multicenter, randomized, crossover study. Chronic corneal edema patients were randomized to one of two arms. The first arm was fitted with the Therapeutic Hyper-CL™ lens ...
The first in-human trials of a novel artificial implant designed to replace dysfunctional corneal endothelium have shown the device to be safe and well-tolerated, according to a study presented at the 25th ESCRS Winter Meeting ...
In contrast, HSV-1 (F)-vaccinated mice developed time-dependent progressive keratitis characterized by corneal opacification, while mock-vaccinated animals exhibited more severe stromal keratitis characterized by immune cell infiltration and neovascularization in corneal stroma with corneal opacification. ...
EyeYon's new product, now on an accelerated path as a Breakthrough Device, is an Artificial Endothelial Layer - EndoArt® - a polymer film implant, attached to the posterior corneal surface, to treat chronic corneal edema secondary to endothelial dysfunction. ...
Mojo Vision's smart contacts put text in my eye and let me see in the dark. The company is aiming for even more than that. There aren't many meetings in Las Vegas during CES that still make my jaw drop. The few I can think of mostly involved Oculus. I had no idea what a company I've never met with before, called Mojo Vision, was going to show me. I knew they made very, very small displays. I ...
What is 19C27? Description LZQ is an OEM factory for all kinds of medical tools, such as Profile Drill P144, Dental Milling Bur/ Zirconia Bur P245, High Precision Fittings P76, Abutment/Transfer P25, ect. We can produce a whole kit of tools for customers' surgical cases. Product Details A complete line of Ophthalmic Surgical Knives includes Stab Knife, Slit Knife and Clear Cornea Knife, ...
Here, we tested a prophylactic live-attenuated vaccine against herpes simplex virus type 1 (HSV-1), a widespread human pathogen that can cause corneal blindness. Parenteral vaccination of mice resulted in sterile immunity to subsequent HSV-1 challenge in the cornea and suppressed productive infection of the nervous system. ...
The aim is to provide the highest Oxygen permeation rate to maximise corneal oxygenation which directly corresponds to comfort and visual performance. ...
The aim of this work was to investigate the influence of the eyelid on the absorbed dose distribution in eye tissues. The study was performed using two versions of the female adult head phantom (FeH) connected to the GEANT4 Monte Carlo code: one has the eyes open and the second, closed. The calculations of organ dose, normalised to air KERMA free-in-air, were done for external exposures to photon ...