Disease Patients Articles & Analysis
58 articles found
Glycated collagen mainly exists in various tissues in the human body, especially those rich in collagen, such as skin, bones, joints, blood vessels, and other connective tissues.Under normal physiological conditions, glycation occurs as a natural biochemical process, but its degree is usually low. In certain disease states, especially in patients with diabetes, ...
Although frontline treatment of chemotherapy and surgery is often effective, with nearly all patients experiencing remission, over 80% of patients will experience disease recurrence in the first two years and ultimately die of the disease. ...
One of the biggest challenges clinical data management faces is the sheer amount of data that needs to be processed. With more and more patient data becoming available, it can be difficult for CDM systems to keep up. ...
ByClinion
Rare diseases, also known as orphan diseases, affect a small percentage of the population, making them particularly challenging to diagnose and treat. ...
Abnormalities in Chromosome Number More or less chromosomes can lead to the occurrence of some rare diseases. Patients with Down syndrome show abnormal mental development and multiple organ malformations due to the presence of an extra chromosome 21. ...
This technology has enabled healthcare professionals to pinpoint the cause of rare diseases more accurately and tailor treatments specific to each patient's genetic makeup. ...
The field of medical science has long utilized disease models, which are systems simulating the progression and expression of a disease, to better understand various illnesses. ...
The field of medical science has long utilized disease models, which are systems simulating the progression and expression of a disease, to better understand various illnesses. ...
When studying gene expression, researchers often compare gene expression profiles between different biological samples or experimental conditions, such as healthy and diseased tissues, treated and untreated cells, or different developmental stages. ...
When studying gene expression, researchers often compare expression profiles across different biological samples or experimental conditions, such as healthy and diseased tissues, treated and untreated cells, or different developmental stages. ...
Actively exploring other proteins of PROTAC in indications such as IRAK4 and other autoimmune diseases will help to develop broader application prospects of this technology. ...
As early as 2013 and 2019, it has been approved by FDA for the adjuvant therapy of HER2-positive advanced breast cancer patients who have received trastuzumab and paclitaxel chemotherapy and HER2-positive early breast cancer patients who have residual HER2-positive early breast cancer patients after receiving taxa and trastuzumab neoadjuvant ...
All we know is that these diseases are not secondary. Doctors used to study these diseases by monitoring patients' vital signs and analyzing laboratory test results. ...
People living with frontotemporal dementia, or FTD, are commonly misdiagnosed with psychiatric disorders or Alzheimer’s disease and other causes of dementia, such as Parkinson’s disease and vascular dementia. While frontotemporal dementia and Alzheimer’s disease can both cause dementia, there are distinct differences in impacted regions of the brain and, consequently, ...
According to the statistics of the deaths of COVID-19 patients in China by the Chinese Center for Disease Control and Prevention , the mortality rate of COVID-19 patients with diabetes underlying diseases is 7.3%, which is 7 times higher than that of patients without any underlying diseases. ...
Defining an Analytics Platform for Derisking Genome Editing Therapies References Intellia’s NTLA-2002 Trial: A One-Time Treatment for Hereditary Angioedema (HAE) An interim readout from the company’s phase I/II trial, testing drug candidate NTLA-2002, demonstrated a reduced occurrence of swelling attacks by 91% in patients with a rare condition called hereditary ...
Failure of Medical Therapy in ADHF: an Ode to the Kidneys The pathophysiology of fluid retention in ADHF in patients with advanced disease has been detailed previously (Figure 2A).21 In brief, reduced circulating blood pressure and cardiac output due to impaired contractility activates baroceptors, stimulates the renin-angiotensin-aldosterone system, and ...
Current guidelines recommend adjuvant treatment only for selected patients with stage II or higher disease. A prediction model that identifies patients at high risk of recurrence who may benefit from adjuvant treatment is greatly needed. ...
Patient History 83 year old male with no history of esophageal disease. The patient was referred to Dr. Singh after a possible esophageal mass was noted as an incidental finding during a CT scan for an unrelated ...
A cyclo-ergometer exercise test was performed on this 57-year old male patient. He is a smoker with a family background of CAD. He is suffering from left bundle branch block making ST-segment analysis impossible. The patient has achieved 78 % of max. heart rate at 120 watts. Moderate paleness and dyspnoea have been observed at the end of the 120 watts step. However, after a normal initial ...