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Disease Resistance Articles & Analysis

17 articles found

Drug Screening in Drug-Resistant Cells: A Critical Approach to Overcoming Treatment Challenges

Drug Screening in Drug-Resistant Cells: A Critical Approach to Overcoming Treatment Challenges

In recent years, the rise of drug-resistant cells has emerged as one of the most significant challenges in the field of medicine, particularly in oncology and infectious diseases. The effectiveness of current therapies is often hindered by the ability of certain cell populations to develop resistance, leading to treatment failure and ...

ByCreative Biogene


Genome Editing in Model Plants: A Paradigm Shift in Plant Science

Genome Editing in Model Plants: A Paradigm Shift in Plant Science

Applications of genome editing in model plants include enhancing disease resistance, increasing stress tolerance, and optimizing growth characteristics. In Arabidopsis, for instance, scientists have successfully edited genes to confer resistance to various pathogens. In rice, genome editing has enabled the development of strains with improved ...

ByCreative Biogene


Clonality Analysis Service: A Paradigm Shift in Disease Diagnosis and Treatment

Clonality Analysis Service: A Paradigm Shift in Disease Diagnosis and Treatment

This knowledge is vital when developing therapeutics, such as vaccines, or studying disease progression and drug resistance. Clonality analysis services also play a central role in quality control in biotechnology. ...

ByCreative Bioarray


Unveiling the Potential of Premade RNA-LNP Products

Unveiling the Potential of Premade RNA-LNP Products

Here, they could potentially enable gene editing in plants to increase resistance to diseases and pests, improve yield, and create more nutritive output. ...

ByCreative Biogene


The Liposome-Based PROTAC Strategy

The Liposome-Based PROTAC Strategy

Candidate drugs like ARV110 and ARV-471 have entered Phase I/II clinical trials, indicating the potential of PROTACs in the treatment of cancer and other diseases. The high selectivity, resistance-overcoming capabilities, and ability to target previously undruggable proteins make PROTACs effective in various diseases, including neurological ...

ByBOC Sciences


Clonality Analysis Service: A Paradigm Shift in Disease Diagnosis and Treatment

Clonality Analysis Service: A Paradigm Shift in Disease Diagnosis and Treatment

This knowledge is vital when developing therapeutics, such as vaccines, or studying disease progression and drug resistance. Clonality analysis services also play a central role in quality control in biotechnology. ...

ByCreative Bioarray


Single Guide RNA Libraries: Their Applications and Future Potential in Biotechnology

Single Guide RNA Libraries: Their Applications and Future Potential in Biotechnology

For instance, sgRNA libraries can facilitate scientists to uncover genes that may contribute to tumor growth or resistance to chemotherapy, offering the prospect for the discovery of innovative cancer therapeutics. In addition, sgRNA libraries possess bright prospects in the realm of infectious diseases. They can prove invaluable in determining host genes ...

ByCreative Biogene


Identifying a combination benefit of a Ph-3 drug with an SOC drug In collaboration with big pharma - Case Study

Identifying a combination benefit of a Ph-3 drug with an SOC drug In collaboration with big pharma - Case Study

The Challenge: To understand the molecular effect of a ph-3 drug (Drug A) which showed moderate outcomes and to recommend next steps to increase response ...

ByCytoReason


LncRNA Sequencing Helps to Find Deep Links to Disease

LncRNA Sequencing Helps to Find Deep Links to Disease

RNA Sequencing Pulls Insights in LncRNA A growing number of genetic studies have linked lncRNA gene aberrations to the development of human diseases. However, a protein-centric view of human disease does not fully capture the complexity of the molecular pathogenesis regulated by lncRNAs. ...

ByCD Genomics


CD Genomics Perspective: Using RNA Sequencing Technology to Study Ecology

CD Genomics Perspective: Using RNA Sequencing Technology to Study Ecology

This can be applied to other ecologically important traits, such as disease resistance and mating behavior, as well as identify genes with potential adaptive significance in changing environments. ...

ByCD Genomics


Targeted Therapy of Intracellular Oncoproteins by Peptide-centered CAR T Cells

Targeted Therapy of Intracellular Oncoproteins by Peptide-centered CAR T Cells

Historically, treatments for neuroblastoma have been chemotherapy, surgery, and radiotherapy, but patients frequently relapse in the form of chemo resistant disease. In addition, the low mutational burden of cancer, coupled with its low MHC expression, makes it difficult for immunotherapy to target therapy. ...

ByCreative BioMart


Increased Disease Resistance Against Rust Fungi & Greater Vigor in Coffee -  Case Study

Increased Disease Resistance Against Rust Fungi & Greater Vigor in Coffee - Case Study

Details:The Kyminasi Plant Booster (KPB) technology was installed on a field of three coffee cultivars, including Colombia, Caturra, and Castillo, in the country of Colombia. The field had been under cultivation for six years and part of the field was under renovation. The field was managed without any ...

ByHarvest Harmonics Corp


Bacterial Coldwater Disease

Bacterial Coldwater Disease

Synonyms Rainbow Trout Fry Syndrome (RTFS) Bacterial fry anemia Low temperature disease Peduncle disease Saddleback Tail-rot Systemic myxobacteriosis Cause of the Disease Bacterial Coldwater Disease (BCWD) is caused by Flavobacterium psychrophilum, also known as Flexibacter psychrophilus and Cytophaga psychrophila. There may be strain differences among isolates but their importance ...

ByTroutlodge, Inc. - part of Hendrix Genetics


Performance of improved Cassava genotypes for early bulking, disease resistance, and culinary qualities in an inland valley ecosystem

Performance of improved Cassava genotypes for early bulking, disease resistance, and culinary qualities in an inland valley ecosystem

While cassava bacterial blight severity (CBBS) was low and not significant, 11 of the genotypes (including two landraces) showed moderate to resistant expression of cassava mosaic disease (CMD) symptoms. Though the genotypes showed moderate damage due to cassava green mite (CGM), fresh root yields obtained from the top performers (92/0427, 91/02327, 91/02322, ...

BySoil Science Society of America (SSSA)


New and diverse sources of multiple disease resistance in Wheat

New and diverse sources of multiple disease resistance in Wheat

On the basis of disease reactions, 88 wheat accessions exhibited resistance to both diseases. Data from the Germplasm Resources Information Network (GRIN) were examined for the 88 accessions to identify those that also have resistance to other key diseases and on this basis 28 accessions with multiple ...

BySoil Science Society of America (SSSA)


Multidrug resistance in fungi

Multidrug resistance in fungi

This has led to obvious concern about the continuing efficacy of antibiotics to control infectious disease (1). Resistance to antibiotics in pathogenic fungi is a problem of special importance in the control of infections caused by these organisms. ...

ByAmerican Society for Microbiology (ASM)


Multidrug resistance in fungi

Multidrug resistance in fungi

This has led to obvious concern about the continuing efficacy of antibiotics to control infectious disease (1). Resistance to antibiotics in pathogenic fungi is a problem of special importance in the control of infections caused by these organisms. ...

ByAmerican Society for Microbiology (ASM)

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