Drug Discovery Research Articles & Analysis
15 articles found
In the realm of drug discovery, kinase screening services have emerged as a pivotal tool for understanding complex cellular signaling pathways and identifying potential therapeutic targets. ...
High-throughput screening (HTS) has become a cornerstone of drug discovery, allowing researchers to rapidly test thousands of compounds for their ability to activate or inhibit specific nuclear receptors. ...
Genomic engineering in cell lines is a versatile tool for studying gene function, designing diseases models, biopharmaceutical research, drug discovery and many other applications. CRISPR (Clustered Regulatory Interspaced Short Palindromic Repeats)/Cas9 systems is a newly developed yet the most popular method for genome editing. ...
They are essential in unraveling the molecular mechanisms underlying cell death and are instrumental in drug development, cancer research, and developmental biology. Types of Apoptosis Assays Morphological Assays: These assays examine the characteristic morphological changes that occur during apoptosis. ...
The reporter gene is essentially a marker that researchers can easily detect, thereby inferencing the activity of the gene of interest. ...
Applications of Glycan Arrays Glycan arrays have found numerous applications in various fields of research, including glycobiology, immunology, and drug discovery. Here are some key areas where glycan arrays have made significant contributions: Glycan-Protein Interactions: Glycan arrays allow researchers to study the specific ...
Expansion in Therapeutic Applications Stable cell lines that possess inducible expression systems can play a vital role in drug discovery research and in vivo/divitro studies, especially in terms of proteomics and genomics. The regulation and controlled expression of specific genes can aid in screening potential drug molecules ...
This analysis is crucial for several reasons: Efficient Target Identification: Identifying the right biological targets is the first step in drug discovery. Through computational analysis, researchers can sift through vast biological data to pinpoint potential targets for drug development. ...
Applications of Molecular Dynamics Simulation Drug Discovery: Molecular dynamics simulation plays a crucial role in drug development. By simulating the interactions between drug molecules and target proteins, it enables the prediction of binding modes, affinity, and stability, thereby guiding the design and optimization of ...
In the fast-paced realm of drug discovery, scientists constantly seek innovative approaches to efficiently and cost-effectively identify potential drug candidates. ...
Structural biology is an important field in drug discovery as it helps researchers understand the three-dimensional structure of proteins and how they interact with other molecules. This knowledge is crucial in developing new drugs as it allows scientists to target specific proteins and understand how they contribute to diseases. ...
Published by Vijay K Singh and Thomas M Seed on September 3, 2021, in Expert Opinion on Drug Discovery and deals with the necessity of animal models for modern drug research in the direction of animal strains, animal models, requirements, and pathways for developing new drugs. ...
Mark discusses bit.bio's software approach to biology and how human cells that are programmed like computers can impact research, drug discovery and cell ...
Bybit.bio
Recursion is focused on solving very hard problems in biology and revolutionizing the drug discovery process using computer science. As a computer engineer with almost 20 years of experience in software engineering and a PhD focused on identifying RNA binding protein targets using machine learning, a career at Recursion felt like a hand in a glove. ...
Only by ensuring the entire process is error-free, can researchers devoted to discovering new drugs eventually obtain the ideal drug with safety, effectiveness and controllability. ...