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Drug Resistant Articles & Analysis: This-Year
6 articles found
Challenges and Current Research Directions Despite significant progress, several research challenges in BCL2 biology remain. One of the key issues is drug resistance. Cancer cells often develop resistance to BCL2 inhibitors by upregulating other anti-apoptotic proteins like MCL1 or BCL-XL. ...
This knowledge can help to identify new targets for drug development and understand the genetic basis of diseases. Disease Modeling: Custom knockout cell lines can mimic specific diseases by disabling genes associated with particular disorders. This modeling can be invaluable for studying the pathophysiology of diseases such as cancer, neurodegenerative disorders, and metabolic ...
Understanding Drug Resistance Drug resistance occurs when cancer cells or pathogens evolve mechanisms that render them less susceptible to the effects of therapeutic agents. ...
These cell lines serve as essential models for studying the biology of colorectal cancer, testing new therapies, and exploring the mechanisms of drug resistance. What are Colorectal Cancer Cell Lines? Colorectal cancer cell lines are cultured cells derived from tumor tissues of patients diagnosed with colorectal cancer. ...
Pharmaceuticals: In medicine, lysozyme has been formulated into treatments for infections, inflammation, and even wounds due to its bactericidal and anti-inflammatory properties. It is also employed in drug formulations to enhance drug delivery systems by breaking down bacterial barriers in target tissues. ...
These cutting-edge solutions are grounded in a comprehensive understanding of molecular biology and DNA damage response mechanisms, providing researchers with robust tools to enhance experimental therapies and address drug resistance. “Our small molecule PARPi and PARP peptide inhibitor development services reflect our unwavering commitment to advancing oncology ...