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Hematopoietic Stem Articles & Analysis
11 articles found
When PD-1 molecules on platelets interact with anti-PD-1 on tumor cells they release drugs that eliminate regulatory T cells while boosting CD8+ T cell functions which helps decrease tumor recurrence and metastasis after surgery. Certain researchers joined hematopoietic stem cells (HSC) with platelets modified with anti-PD-1 antibodies (aPD-1) and delivered them ...
They stimulate the proliferation and differentiation of hematopoietic stem cells into various blood cell lineages. Wound Healing: Cytokines are essential for orchestrating the wound healing process. ...
Compared with traditional chemotherapy and hematopoietic stem cell transplantation, it is more precise in killing tumor cells and significantly reduces toxic side effects while improving efficacy. ...
Welcome to our newest blog series where we investigate Amyotrophic Lateral Sclerosis (ALS) using our AI knowledge mapping tools. Check back for our next installment, in which we analyze transcriptomics from spinal cord samples collected from patients as well as a mouse model. In this post, we will continue to explore publicly available datasets surrounding Amyotrophic Lateral Sclerosis ...
ByPercayAI
Many cell and gene therapy solutions have shown considerable promise as a source of possible treatments for a wide range of chronic disorders. However, these sophisticated therapies introduce additional barriers such as the requirements for ultra-low and cryogenic storage, which affect numerous steps of the biomedical solutions’ life cycles, from their development to their administration. ...
The blood stem cells she received had a mutation called "CCR5Δ32/Δ32," which protects T cells from infection. ...
Colony stimulating factor (CSF) is a cytokine that stimulates the proliferation and differentiation of pluripotent hematopoietic stem cells, etc., to form corresponding cell clones in semi-solid medium. ...
The authors report that STAT1KO mice spontaneously develop inflammatory diseases characterized by bone marrow hyperplasia and splenic accumulation of hematopoietic stem cells. In addition, these animals developed inflammatory bowel disease. ...
What is your background and experience in the regenerative medicine and stem cell space? How did this lead you to Regeneus? A. I have always been fascinated by Medical Science, especially the regenerative medicine and stem cell fields. ...
Notch1 and RBP-j are critical for the specification of hematopoietic stem cells (HSCs) in Notch signal-receiving cells. However, the mechanism by which Notch signaling is triggered from the Notch signal-sending cells to support embryonic hematopoiesis remains to be determined. ...
The microRNAs were shown to target their predicted sites within the homeobox. miR-126 and Hoxa9 mRNA are coexpressed in hematopoietic stem cells and downregulated in parallel during progenitor cell differentiation; however, miR-145 is barely detectable in hematopoietic cells, and let-7s are highly expressed in bone marrow progenitors, suggesting ...