Immune Evasion Articles & Analysis
12 articles found
Immuno-oncology is an innovative field that utilizes the body’s immune system to combat cancer. By harnessing the natural capabilities of the immune system, immuno-oncology services are revolutionizing the way we approach cancer treatment, offering novel therapies that are changing the prognosis for many patients. Understanding Immuno-Oncology ...
For instance, sphingolipids in exosomes are implicated in cancer progression by promoting exosome-mediated signaling that enhances tumor cell proliferation and immune evasion. Researchers have found that alterations in exosomal lipid profiles can be a hallmark of disease. ...
Clinical Advantages of Bispecific Antibodies Compared with ordinary antibodies, BsAb adds a specific antigen-binding site and shows the following advantages in treatment: Mediating immune cell killing of tumors: An important mechanism of action of bispecific antibodies is to mediate immune cell killing. ...
Vaccines are considered one of the most successful medical interventions in the past few centuries, aiming to harness the human immune system and generate lasting protection against specific diseases. ...
Its primary function revolves around converting extracellular ATP into immunosuppressive adenosine, working in tandem with CD39 within normal tissues to curtail excessive immune reactions. However, this mechanism is often hijacked by tumors, utilizing CD73 to foster an adenosinergic process that shields them from immune assaults. ...
It is also a primary target for host immune surveillance and tactics for human interference. Initially, coronaviruses connect to a cell surface receptor to enter host cells for viral binding, then enter endosomes, and eventually combine the viral and lysosomal membranes. ...
CADM molecules, particularly CADM1, have been implicated in tumor immune escape due to their involvement in immune cell interactions and regulation of immune responses. ...
Viral vector vaccines have also attracted attention in recent years because of their potential to induce strong and long-lasting immune responses, including adenoviruses, retroviruses, lentiviruses, and poxviruses. ...
It is involved in the formation and development of the tumor microenvironment (TME) and plays an important role in regulating immune responses. Researchers state that enoblituzumab, as a new treatment approach, primarily works by relieving the inhibition of the immune system's recognition and elimination of cancer cells by B7-H3. ...
So which cells are best used for immunotherapies? Immune Checkpoint Inhibitors Controlling the strength and amplitude of an immune response is a critical feature of a healthy immune system. ...
The interesting SARS-CoV-2 omicron mutant strain evades immunity mediated by antibodies from vaccination or infection with early mutants due to the accumulation of a large number of spike mutations. Recently, in a research report titled "Structural basis of SARS-CoV-2 Omicron immune evasion and receptor engagement" published in Science, ...
The challenges of evading both pre-existing immunity and de novo adaptive immune responses against AAV vectors are made especially difficult by the heterogeneous nature of patient immune responses and immune histories. ...