In Vitro Study Articles & Analysis: This-Year
9 articles found
Abstract Cannabis is used by an estimated 192 million people around the world. Most people use cannabis through the inhalation of cannabis smoke, which contains combustion by-products that can negatively affect lung health. Knowledge of these risks has led to a growing interest in cannabis vaporizers, which heat the dry cannabis flower without burning. Vaporizing cannabis still releases ...
The development of recombinant MGP protein has enabled researchers to study the molecular mechanisms of calcification control and evaluate therapeutic interventions in a variety of disease contexts. ...
Traditional investigations of podocytes have faced challenges due to their limited in vitro lifespan. Primary podocyte cultures tend to proliferate for only a brief period, making it difficult to conduct long-term studies on their behavior or response to therapeutic agents. ...
One of the most widely recognized in vitro models for evaluating the intestinal absorption of compounds is the Caco-2 permeability assay. ...
Scientists discovered that platelets can engulf bacteria which opens a new pathway for administering drugs non-invasively using platelets as carriers. Some studies have examined drug delivery systems using platelet endocytosis to absorb fluorescent beads and viral particles which get stored in platelet α-granules for subsequent release during platelet activation. During in ...
These approaches often include in vitro and in vivo testing, as well as computational modeling. In vitro testing involves studying immune responses in controlled laboratory environments using cell cultures. ...
Animal models offer researchers valuable insights that cannot be obtained through in vitro studies alone, bridging the gap between laboratory research and human application. ...
Types of ADME Testing Services To ensure comprehensive evaluation, various testing methodologies are employed, including in vitro and in vivo studies, alongside computational modeling techniques. ...
Preclinical models are indispensable for advancing our knowledge of NAFLD, as they provide the necessary platforms to study its pathophysiology, test potential therapeutics, and explore its progression to more severe forms like non-alcoholic steatohepatitis (NASH). ...