In Vivo Screening Articles & Analysis
4 articles found
By adding a fifth lipid to the existing prescription of traditional four-component LNPs and adjusting the ratio of this lipid, selective targeting to different organs such as the liver, lung, and spleen can be achieved. After in vivo screening, they found that the traditional four-component LNPs mainly accumulate in the liver and partially in the spleen, while ...
This dual approach was observed to provide higher level of vascularization and new bone formation in vivo. While applied in this case for bone regeneration, this technique could be easily adapted to prevascularise scaffolds to target regeneration of any tissue and organs. ...
ByRegenhu
The US Environmental Protection Agency has responsibility for assessing endocrine activity of more than 10 000 chemicals, a task that cannot reasonably be achieved solely through use of available mammalian and nonmammalian in vivo screening assays. Hence, it has been proposed that chemicals be prioritized for in vivo testing using data from in ...
Sex reversal effects of nonylphenol and bisphenol A on the gonads in F1(AWE × WE) Japanese quail (Coturnix japonica) embryos were investigated using an in vivo screening model developed previously. The F1 (AWE × WE) Japanese quail are a useful avian model because sex differentiation is confirmed by the plumage color before hatching, ruled by a criss‐cross ...