Inflammatory Cytokine Articles & Analysis
25 articles found
What is a Customized Rabbit Cytokine Assay? A Customized Rabbit Cytokine Assay is a specialized service designed to measure the concentration of specific cytokines in rabbit samples. ...
Th1 cells suppress B-cell function and mediate cellular immunity by secreting inflammatory cytokines such as interleukin (IL) and interferon (IFN), and enhance anti-infective immunity by phagocytes. ...
Functionally, TREM1 acts as an amplifier of inflammatory responses. Upon activation, it potentiates the production of pro-inflammatory cytokines, such as tumor necrosis factor-alpha (TNF-α), interleukin-1 beta (IL-1β), and interleukin-6 (IL-6), thereby exacerbating the inflammatory cascade. ...
Luminex technology is a powerful tool for cytokine profiling in oncology research. It is a bead-based assay system that allows the simultaneous measurement of multiple cytokines in a single sample. The technology has revolutionized the field of cytokine research, making it possible to study complex cytokine interactions and ...
Luminex technology is a powerful tool for cytokine profiling in oncology research. It is a bead-based assay system that allows the simultaneous measurement of multiple cytokines in a single sample. The technology has revolutionized the field of cytokine research, making it possible to study complex cytokine interactions and ...
Binding of adjuvants to antigens can increase the surface area of the antigen, and the biological effects include (1) deposit effect of antigen; (2) upregulation of cytokine and chemokine expression, and recruitment of immune cells at the injection site; (3) activation of inflammasome; and (4) carrier effects. ...
Currently, tumor-targeted therapy targeting NF-κB is one of the hot spots in cancer treatment. Detection of inflammatory factors Cytokines have the ability to promote and suppress inflammatory responses, so it is important to understand the complex network of secreted cytokines. ...
It usually binds to its inhibitory protein in a non-activated state in the form of P50-P65 dimer. Many inflammatory responses are strongly associated with NF-κB activation. By combining CPP (8K, octa-yLysine) with NF-κB essential regulator binding domain (NBD), Dave et al. treated mice with inflammatory bowel disease by intraperitoneal injection. The ...
The binding of IL-36 Ra to IL-1R6 does not lead to the recruitment of IL-1RAcP. Therefore, the pro-inflammatory cascade reaction is not initiated, realizing the anti-inflammatory characteristics of IL-36 Ra. ...
Analysis of tissue staining and immunohistochemistry showed that the natural hydrogel significantly accelerated the granulation tissue regeneration, angiogenesis and collagen deposition in chronic wounds, and significantly down-regulate the expression levels of TNF-α, IFN-γ, IL-6 and other inflammatory cytokines in tissues. In-depth mechanistic ...
It’s reported that persistent activation of NF-κB can lead to chronic inflammation, such as rheumatoid arthritis, Parkinson's disease, and inflammatory bowel disease. However, NF-κB activation requires interactions with NF-κB essential modulators and kinase complexes. A test was carried out by combining CPP (8K, Octylysine) with NF-κB essential ...
Disambiguation The process of stimulating the Vagus Nerve with micropulses of electrical current is referred to in a number of different ways. Vagus Nerve Stimulation (VNS) - Typically refers to stimulation of the nerve with a surgically implanted device and electrode. Non-invasive Vagus Nerve Stimulation (tVNS, taVNS, nVNS, LLTS) - Refers to stimulation of the vagus nerve without ...
Hypertrophy and hyperplasia of the adipocytes result in metabolic alterations and in the onset of a low grade chronic inflammatory state (14) due to the release of pro-inflammatory adipokines from adipose tissue that can trigger insulin resistance and diabetes mellitus leading to a sequentially increased cardiovascular risk (15). ...
Cytokines are classified according to their different roles in the inflammatory response: pro-inflammatory cytokines and anti-inflammatory cytokines. Pro-inflammatory Cytokines Interleukin-1 (IL-1) IL-1 is a proinflammatory cytokine that ...
Patients with psychiatric problems have a profile of enhanced pro-inflammatory cytokines and increased oxidative stress, according to data. ...
The world's leading researchers joined Immunai’s second symposium dedicated to applications of Machine Learning (ML) in biology. The line-up of talks demonstrated innovative research taking place at the intersection of immunology and machine learning. ML is becoming an essential tool in every aspect of immunology. Our speakers shared their work on how they leveraged ML in their research, ...
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At the same time, foreign mRNA can also activate the expression of pro-inflammatory cytokines such as interferon. Classification of mRNA delivery systems 1. ...
Research has discovered that many cytokines and niche factors play a role in the initiation, progression, and remission of inflammation; however, developing an unbiased model that accurately recapitulates the in vivo inflammatory environment is a challenge. ...
Abstract Gut microbiota play a major role in host physiology and immunity. Inflammatory bowel diseases (IBDs), the important immune-related diseases, can occur through immune system malfunction originating due to dysregulation of the gut microbiota. ...
One of the proposed mechanisms for the progression of ALDs is binding of LPS to Toll-like receptor 4 (TLR4) in both Kupffer cells and hepatic stellate cells in the liver, which results in increased hepatic pro-inflammatory cytokines, such as tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β) (Louvet and Mathurin, 2015, Paik et al., ...