insulin sensitivity Articles
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Increased insulin action in skip heterozygous knockout mice
Insulin controls glucose homeostasis and lipid metabolism, and insulin impairment plays a critical role in the pathogenesis of diabetes mellitus. Human skeletal muscle and kidney enriched inositol polyphosphate phosphatase (SKIP) is a member of the phosphatidylinositol 3,4,5-trisphosphate phosphatase family (T. Ijuin et al. J. Biol. Chem. 275:10870-10875, 2000; T. Ijuin and T. Takenawa, Mol. ...
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Glucose Clamp Technique: Types & Applications
Glucose clamping has become a standard, widely used technique in researching diabetes treatment as well as obesity and fatty liver studies. We've taken a look at the types and applications of clamp study and their impact on the field. The Glucose clamp technique was first developed in 1979 by professors at the UT School of Medicine: DeFronzo, Andres and Tobin as a method of measuring insulin ...
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How to support healthy blood sugar levels.
Healthy blood sugar levels are important for everyone. Maintaining healthy blood sugar levels can help reduce the risk of developing diabetes, kidney dysfunction, and problems with your eyes, gums, and nerves. Day-to-day healthy blood sugar levels will help with balancing energy levels, maintaining focus, and stabilizing mood. What Is “Blood Sugar?” Blood sugar, also known as ...
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The Health Effects of Probiotics on the Human Body
Probiotics are a type of active microorganisms that play a role by improving the balance of the host's intestinal microflora. They can produce definite health effects to improve the host's microecological balance and play a beneficial role. In 2001, the World Food and Agriculture Organization (FAO) and the World Health Organization (WHO) also defined probiotics as follows: Live bacteria that can ...
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Hypoglycemic Functional Factors in Natural Products and Their Mechanisms of Action
Diabetes is a common clinical disease, and with the improvement of living standards, an increase in the number of obese people, and the intensification of aging populations, the incidence of diabetes is increasing year by year. Diabetes has various types and requires long-term treatment. Antidiabetic drugs are essential for people with the disease. These drugs can be classified into insulin ...
By BOC Sciences
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The Reality of Diabetes Reversal
The conversation around diabetes reversal has increased, and when researching diabetes there are numerous states to this claim, but how realistic is it? Sadly, diabetes affects a huge number of people worldwide and is responsible for blindness, kidney disease, limb amputation and death. WHO estimates that diabetes was the seventh leading cause of death in 2016[1] and 422 million adults currently ...
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In Silico Development of Combinatorial Therapeutic Approaches Targeting Key Signaling Pathways in Metabolic Syndrome
Purpose Dysregulations of key signaling pathways in metabolic syndrome are multifactorial, eventually leading to cardiovascular events. Hyperglycemia in conjunction with dyslipidemia induces insulin resistance and provokes release of proinflammatory cytokines resulting in chronic inflammation, accelerated lipid peroxidation with further development of atherosclerotic alterations and diabetes. We ...
By VeriSIM Life
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Diabetes: Medications, Treatments, and Remedies
Lifestyle can have a big impact on how your body handles blood glucose and sometimes a change in habits and activities is all that’s needed to prevent or better manage diabetes. But if changes in lifestyle aren’t enough to keep blood sugar levels normal, your doctor may prescribe medication to help lower insulin levels or insulin therapy. We’ll discuss here the most often ...
By Genteel LLC
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