Intestinal Lumen Articles & Analysis
5 articles found
One of the most widely recognized in vitro models for evaluating the intestinal absorption of compounds is the Caco-2 permeability assay. This assay plays a pivotal role in understanding how drugs are absorbed in the gastrointestinal tract and aids in predicting their bioavailability. ...
Enteroendocrine cells have an apical membrane facing the intestinal lumen that allows them to interact with microorganisms and their metabolites. ...
Lactase is a disaccharidase present on the surface of mammalian small intestinal mucosal microvilli, and many beneficial intestinal bacteria have the ability to produce lactase. ...
The large intestine is composed of intestinal epithelial cells (IECs), which form an intestinal barrier between the microbiota in the intestinal lumen and surrounding tissues. ...
Human intestinal stem cells, by contrast, are already epigenetically modified to limit them to a range of differentiated types but are then free to form the appropriate diversity of intestinal epithelial cell types. ...