metabolism improve Articles
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Involvement of the inorganic phosphate transporter Pit1 in insulin signaling and metabolism - Case Study
PiT1, initially identified as retrovirus receptor, is a transmembrane protein of the sodium-phosphate co-transporter family. PiT1 also has independent functions of its role as a phosphate transporter, notably on cell proliferation, adhesion or apoptosis. These observations suggest that interactions of PiT1 with other molecular partners may impact not only the homeostasis of inorganic phosphate, ...
By Inovarion
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Akkermansia muciniphila - Preclinical studies
A large body of evidence suggests that Akkermansia muciniphila may help protect against specific metabolic disorders and cardiometabolic risk factors associated with a low-grade inflammatory status. Indeed, preclinical studies performed in diet-induced obese mice revealed very interesting beneficial effects linked to the daily oral administration of Akkermansia muciniphila. Giving the ...
By A-Mansia
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Oxygen therapy for neurology
A prematurely aged brain has suffered years of abuse from our ever-increasingly toxic environment and unhealthy lifestyles. There is extensive research that shows HBOT may have an effect in rejuvenating a patient’s brain by stimulating the production of new blood vessels. Increased oxygen in the blood flow will re-energize dormant cells in the brain and create new ones. Oxygen to ...
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The Functions and Roles of Enzymes
Catalysis Enzymes are a class of biological catalysts. They govern many catalytic processes such as metabolism, nutrition, and energy conversion of organisms. Most of the reactions closely related to life processes are enzyme-catalyzed reactions. These properties of the enzyme enable the intricate process of material metabolism in the cell to proceed in an orderly manner, and to adapt material ...
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Some Basics about Graphene
Graphene first appeared in the laboratory in 2004. At that time, two British scientists, Andre Geim and Prof Kostya Novoselov, discovered that they could get thinner and thinner graphite flakes in a very simple way. They peeled the graphite flakes from the graphite, and then glued the two sides of the flakes to a special tape. When the tape was peeled off, the graphite flakes were divided in two. ...
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Carbohydrate Synthesis: Understanding the Building Blocks of Life
Carbohydrates are one of the essential macromolecules that play a crucial role in the functioning of living organisms. They serve as a primary source of energy and are involved in various biological processes. The synthesis of carbohydrates is a complex and fascinating process that occurs in living organisms, allowing them to produce and utilize these vital molecules. In this blog post, we will ...
By CD BioGlyco.
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Huateng Pharma Supplies Canagliflozin Intermediates With Commercial Scale Production
Canagliflozin is a medication used to treat type 2 diabetes. It is a third-line medication to be tried after metformin, a first-line medication for type 2 diabetes. It is used together with exercise and diet. It is not recommended in type 1 diabetes. Mechanism action of Canagliflozin Canagliflozin is a sodium-glucose cotransporter (SGLT2) inhibitor. Glucose filtered in the renal tubular lumen is ...
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Treatment for shoulder pain - Case Study
Treatment for shoulder pain Gabi Zeilig, MD, Dept of Neurological Rehabilitation The Chaim Sheba Medical Center, Tel Hashomer, Israel. Purpose of the study: to test the efficacy of the TerraQuant medical device on shoulder pain resulting from inflammation (OA, Tendonitis, Bursitis). Background: TerraQuant is a unique device which combines low level pulse laser therapy (LLLT), pulsating ...
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Introduction to Lipogenesis, Lipid Anabolism and Catabolism
Sources of Fat Fat, also known as triglyceride, is made by condensing one molecule of glycerol and three fatty acids. The source of fatty acids in the body: one is the body's own synthesis, and the other is the food supply. Some unsaturated fatty acids cannot be synthesized by the body and depend on food supply, called essential fatty acids. There are mainly two kinds, one is the ω-3 series ...
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New levodopa therapeutic strategies
Abstract During its almost half-century of use for treating Parkinson's disease, levodopa therapy has permitted most patients to reverse much of this disorder's symptomatology. However, the full range of its therapeutic properties is not completely understood, as levodopa is showing itself to be more than just a metabolic intermediate for dopamine synthesis. Improving the constancy of drug ...
By Sensidose AB
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A Japanese Company Launched A Standing Computer Desk To Prohibit Employees From Sitting Down And Using Computers
In order to improve the efficiency of employees' work, a Japanese company has specially ordered a gray standing table that can only be used for standing, and prohibits employees from using the computer while sitting in a chair. This new office concept is designed to make it easier for employees to focus on their work and prevent employees from working long and inefficiently. The Japanese ...
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High glycolytic flux improves pyruvate production by a metabolically engineered escherichia coli strain
We report pyruvate formation in Escherichia coli strain ALS929 containing mutations in the aceEF, pfl, poxB, pps, and ldhA genes which encode, respectively, the pyruvate dehydrogenase complex, pyruvate formate lyase, pyruvate oxidase, phosphoenolpyruvate synthase, and lactate dehydrogenase. The glycolytic rate and pyruvate productivity were compared using glucose-, acetate-, nitrogen-, or ...
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Big data analytics identifies metabolic inhibitors and promoters for productivity improvement and optimization of monoclonal antibody (mAb) production process
The bioreactor’s environment and media contents affect the metabolism and productivity of a cell line. Traditional analytics like pH, temperature, dissolved gas levels, and titer reveals useful but incomplete information about the cells’ metabolism. Extracellular metabolites and nutrients in the cell media can be monitored to provide some information about the health of the cells. ...
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Exercise in the morning or in the evening has a completely distinct effect!
Life is all about working out. Moderate exercise not only strengthens the body, but also improves the metabolic state and slows the progression of diseases. However, different times of exercise may have different impacts, and it is an intriguing scientific question how to determine the best time to exercise. Although the influence of exercise on energy metabolism is well recognized, there is ...
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Hypoglycemic Functional Factors in Natural Products and Their Mechanisms of Action
Diabetes is a common clinical disease, and with the improvement of living standards, an increase in the number of obese people, and the intensification of aging populations, the incidence of diabetes is increasing year by year. Diabetes has various types and requires long-term treatment. Antidiabetic drugs are essential for people with the disease. These drugs can be classified into insulin ...
By BOC Sciences
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Introduction to Organic Acids
What is an organic acid? Organic acids are organic compounds that are acidic in nature. The most common organic acids are carboxylic acids, with acidity derived from the carboxyl group (-COOH). Sulfonic acid (-SO3H), sulfinic acid (RSOOH), and sulfuric acid (RCOSH) are also organic acids. Organic acids can react with alcohols to form esters. Carboxyl group is the functional group of carboxylic ...
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Nonalcoholic Fatty Liver and How Fucoxanthin Might Help
Many may not have heard of nonalcoholic fatty liver (NAFL) yet it is a very common condition. If NAFL is not addressed, it can progress to a serious condition known as Nonalcoholic fatty liver disease (NAFLD) Non-alcoholic fatty liver is the buildup of extra fat in liver cells that is not caused by alcohol. It is normal for the liver to contain some fat. However, if more than 5% -10% percent of ...
By Algatech
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Why Liver Health is so important? (Or, did you know that in the U.S. 100 million people may have fatty livers?)
Let's face it; the liver is the primary organ in the body that often gets overlooked when it comes to health. According to Traditional Chinese Medicine, the liver is the organ responsible for the smooth flow of emotions, as well as Qi (Energy) and blood. It is the organ that is most affected by excess stress or emotions.Ii] The liver is responsible for numerous functions in the body. Its primary ...
By Algatech
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Emerging therapy for HFpEF: SGLT2 inhibitors
Recent clinical trials investigating sodium-glucose cotransporter 2 inhibitors (SGLT2i) have highlighted that this drug is highly effective in treating patients with heart failure with preserved ejection fraction (HFpEF). HFpEF is a complex disease which accounts for more than half of all heart failure (HF) hospital admissions and is an increasing disease burden. [1] The prevalence of HFpEF is ...
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