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Microvasculature Articles & Analysis

6 articles found

Understanding Skeletal Muscle Microvascular Endothelial Cells: A Crucial Component of Muscle Health

Understanding Skeletal Muscle Microvascular Endothelial Cells: A Crucial Component of Muscle Health

Impaired endothelial function in muscle microvasculature can lead to reduced insulin sensitivity and glucose uptake, further exacerbating metabolic dysregulation. ...

ByCreative Bioarray


Spatial profiling of chromatin accessibility in mouse and human tissues

Spatial profiling of chromatin accessibility in mouse and human tissues

CD144, which encodes vascular endothelial cadherin (VE-cadherin)15, corresponded to endothelial microvasculature near to the crypt or between follicles. CD32, a surface receptor that is involved in phagocytosis and clearing of immune complexes46, and CD55, a complement decay-accelerating factor, were both active in the same region such that the cells that are not supposed to be ...

ByAtlasXomics Inc.


Effect of endothelium mimicking self-assembled nanomatrices on cell adhesion and spreading of human endothelial cells and smooth muscle cells

Effect of endothelium mimicking self-assembled nanomatrices on cell adhesion and spreading of human endothelial cells and smooth muscle cells

Despite recent advances, the generation of a functional microvasculature remains elusive [2,3]. Several types of scaffolds have been used, ranging from synthetic materials, such as Dacron [4], to natural ECM proteins, such as collagen [5]. ...

ByEndomimetics


High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue

High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue

Application to mouse embryos revealed major tissue types in early organogenesis as well as fine features like microvasculature in a brain and pigmented epithelium in an eye field. Gene expression profiles in 10-μm pixels conformed into the clusters of single-cell transcriptomes, allowing for rapid identification of cell types and spatial distributions. ...

ByAtlasXomics Inc.


What is the meaning of neoplastic disease?

What is the meaning of neoplastic disease?

Neoplasia is the abnormal growth and proliferation of abnormal cells or abnormal amounts of cells due to a benign or malignant process. There can be benign tumors, or neoplasms, and malignant ones. Remember that it's the malignant tumors, or cancer, that can metastasize, which is when cancer spreads around the body. Leukemia is used for lymphoid neoplasms presenting with widespread involvement ...

ByStelvio Oncology


Microfluidic tools to investigate pathologies in the blood microcirculation

Microfluidic tools to investigate pathologies in the blood microcirculation

Examples of applications are given in the context of the acute respiratory distress syndrome (ARDS), an inflammatory disease of the lung triggered by a massive arrest of white blood cells in the lung microvasculature. The main challenge consists in building relevant micro–devices to reproduce key biological characteristics of blood capillaries. ...

ByInderscience Publishers

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