Mitochondrial Membrane Articles & Analysis
9 articles found
The BCL2 gene encodes an integral membrane protein that blocks apoptotic cell death. It was originally discovered in follicular B-cell lymphoma, where a chromosomal translocation (t(14;18)(q32;q21)) leads to its overexpression. ...
ATP Yield MeasurementDirectly measure the amount of ATP produced in the cell or mitochondrial preparation. This can be achieved by various biochemical methods, such as ATP-dependent enzyme reactions.4. ...
One such assay is the fluorescent microscopy-based analysis of cell nuclei and mitochondria, where apoptotic cells exhibit condensed and fragmented nuclei, along with altered mitochondrial membrane potential. Viability Assays: Quantifying cell viability is crucial to determine the extent of apoptosis. Common viability assays include the MTT assay, which ...
CYP enzymes can be classified according to the membrane-bound and soluble forms. In prokaryotes, CYP450 is a soluble protein. In eukaryotes, they are usually bound to the endoplasmic reticulum or inner mitochondrial membranes. CYP450 can also be classified into four classes based on electron transfer processes, depending on how electrons from ...
These protein components are mainly encoded by the nuclear genome, which accounts for about 1/3 of the mitochondrial proteome. studies have speculated that the nuclear genome encodes about 250 proteins that play an important role in maintaining the expression of the mitochondrial genome. Mitochondria are dynamic organelles with a bilayer ...
Cardiolipids Altering fatty acid synthesis and modification can also affect the function of organelles within membrane-containing cells by altering the composition of specific membrane lipids. Cardiolipids are structurally unique phospholipids located primarily in the inner mitochondrial membrane, where they control ...
Adenosine triphosphate/adenosine diphosphate (ATP/ADP) ratios, reduced/oxidized nicotinamide adenine dinucleotide (NADH/NAD+) ratios, mitochondrial membrane potential (△ψm) and energy production related mRNA expressions increased in the ovary after 10 days of Cd treatment and decreased after 20 days. ...
Specific septins localized to the outer mitochondrial membrane, to septa formed during mitochondrial scission, or to the mitochondrion-associated endoplasmic reticulum. ...
The motif Cys residues are functionally important and appear to be present in disulfide linkages within a large oligomeric complex associated with the mitochondrial inner membrane. The import of Pet191 differs from that of other twin-Cx9C motif class of proteins in being independent of the Mia40 ...