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Mitochondrial Respiration Articles & Analysis

4 articles found

Novel Mechanism of Glycosylation Regulating Pancreatic Cancer Reveled

Novel Mechanism of Glycosylation Regulating Pancreatic Cancer Reveled

In addition, MDH1 is involved in the intracellular malate-aspartate shuttle pathway that coordinates glycolysis and mitochondrial respiration; MDH1 glycosylation will facilitate the regeneration of NADH, thereby promoting mitochondrial respiration. ...

ByCD BioGlyco.


Fatty Acids in Cancer

Fatty Acids in Cancer

Cardiolipids are structurally unique phospholipids located primarily in the inner mitochondrial membrane, where they control mitochondrial respiration and act as a signaling platform in the induction of apoptosis. 3、Protein acylation The abundance and saturation of cellular fatty acids determine the activity of signaling proteins that require ...

ByCreative Proteomics


Fipronil and imidacloprid reduce honeybee mitochondrial activity

Fipronil and imidacloprid reduce honeybee mitochondrial activity

Fipronil caused dose‐dependent inhibition of adenosine 5′‐diphosphate–stimulated (state 3) respiration in mitochondria energized by either pyruvate or succinate, albeit with different potentials, in thoracic mitochondria; inhibition was strongest when respiring with complex I substrate. ...

ByJohn Wiley & Sons, Ltd.


Function of heterologous mycobacterium tuberculosis inha, a type 2 fatty acid synthase enzyme involved in extending c20 fatty acids to c60-to-c90 mycolic acids, during de novo lipoic acid synthesis in saccharomyces cerevisiae

Function of heterologous mycobacterium tuberculosis inha, a type 2 fatty acid synthase enzyme involved in extending c20 fatty acids to c60-to-c90 mycolic acids, during de novo lipoic acid synthesis in saccharomyces cerevisiae

Here, the genes for InhA (Rv1484) and four similar proteins (Rv0927c, Rv3485c, Rv3530c, and Rv3559c) were expressed in S. cerevisiae etr1 cells lacking mitochondrial 2-trans-enoyl-thioester reductase activity. The phenotype of the yeast mutants includes the inability to produce sufficient levels of lipoic acid, form mitochondrial cytochromes, ...

ByAmerican Society for Microbiology (ASM)

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