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Neurodegenerative Diseases Articles & Analysis: This-Year
6 articles found
One notable study published in Nature Neuroscience (2021) demonstrated how CX3CL1-fractalkine signaling influences microglial activity in neurodegenerative diseases like Alzheimer’s. These findings suggest potential avenues for therapeutic intervention targeting neuroinflammation. ...
They have applications in basic biology research, as well as in fundamental processes for drug discovery, disease modeling, regenerative medicine, and personalized treatment approaches. ...
This is particularly crucial for developing targeted therapies and understanding disease mechanisms, as many neurological disorders exhibit species-specific features that limit translatability. Applications in Research HA-c can be employed in various research applications, including: Disease Modeling: By exposing HA-c to pathogenic factors or genetic ...
This groundbreaking approach unlocks new potential in targeting previously “undruggable” proteins, paving the way for transformative therapies in various diseases. At the forefront of this innovation are specialized PROTAC discovery and screening services, which streamline the pathway from concept to clinical application. ...
This approach is especially beneficial for investigating diseases with immune dysregulation, such as cancer, autoimmune disorders, or infectious diseases, where multiple cytokines orchestrate pathological processes. ...
Moreover, lipidomic shifts can also reveal insights into metabolic conditions such as obesity, diabetes, and neurodegenerative diseases. For instance, certain lipid species found in exosomes may indicate disrupted signaling pathways or abnormal cellular function, providing opportunities for therapeutic intervention. Metabolomics in Exosome Function and ...