Neurological Diseases And Disorders Articles & Analysis: Older
23 articles found
They are implicated in a wide range of conditions, from cardiovascular and metabolic disorders to neurological diseases and cancers. By facilitating the early stages of the drug development pipeline, GPCR Screening Services help streamline the identification of lead compounds, optimizing the chances of successful therapeutic outcomes. ...
Benefits and advantages of iPSC differentiation to neural stem cells (NSC), neurons and glial cells: Provides genetic and physiologically relevant in vitro models to study neural development and associated disorders: congenital disorders, neurodegenerative disorders and brain tumors. Generates a valuable model for identifying new targets for ...
Candidate drugs like ARV110 and ARV-471 have entered Phase I/II clinical trials, indicating the potential of PROTACs in the treatment of cancer and other diseases. The high selectivity, resistance-overcoming capabilities, and ability to target previously undruggable proteins make PROTACs effective in various diseases, including neurological ...
CD Genomics, a well-established leader in transcriptome solutions, is pleased to announce the introduction of Ribosome Profiling technology. This innovative technique promises to provide valuable insights into gene expression, protein synthesis, and regulation, offering potential advancements in the field of RNA translation research. Ribo-seq is a cutting-edge high-resolution sequencing ...
Their immune-modulatory abilities make them a sought-after tool in treating autoimmune diseases, while their differentiation potential is harnessed for tissue repair and regeneration. In a clinical context, MSCs are instrumental in treating osteoarthritis, inflammatory bowel disease, graft-versus-host disease, myocardial infarction, and more. ...
Chimeric RNAs have been observed in various organisms, including humans, and have been found to play a role in a variety of diseases, particularly cancer. They can contribute to tumorigenesis by generating abnormal proteins or disrupting normal cellular processes. Chimeric RNAs have also been implicated in other diseases, such as neurological ...
It contributes extensively to the understanding of the physiological function of ionic channels in health and disease. From exploring their roles in some neurological disorders, cardiovascular diseases to electrolyte imbalance—it's a resourceful tool. ...
More than a dozen viral gene therapy products have been approved for the treatment of cancer, infectious diseases, and rare single-gene disorders. The main types of viral vectors used clinically for in vivo gene therapy include adenovirus, adeno-associated virus (AAV), herpes simplex virus (HSV), retroviruses, and lentiviruses. ...
In late November, EpiFinder Co-Founder Neel Mehta and Creative Officer Kristi Kietzmann left Arizona for a cross-country road trip. The journey from Arizona to Washington D.C. covered 5,504 miles over 22 days. At Washington D.C., CEO Robert Yao and other team members joined them for the 71s American Epilepsy Society (AES) conference. There, the team held 3 days of exhibits and presented. Why ...
Thereby, those changes include DNA methylation, histone modifications and non-coding RNAs. affects gene regulation. Diseases And Epigenetic Modifications The occurrence of some diseases has been found to be inextricably linked to epigenetics. ...
Several improvements support the hypothesis that dynamic standing using the Innowalk is effective as an add-on to standard therapy in the treatment of children and young people with severe motor impairments. The study included 46 patients where 50% were diagnosed with cerebral palsy and 50% with diverse syndromes. The results show improvements on: Passive assisted motion (79%) Stimulation ...
The discovery could lead to better new treatments for neurological disorders such as anxiety, autism spectrum disorder, schizophrenia and Parkinson's disease. In determining the structure of this transporter, one of the smallest proteins ever made, researchers have opened up new avenues to improve drugs for a variety of ...
The relationship between lncRNAs and diseases is well established, especially in chronic disorders. However, cancer is one of the most intensively studied diseases associated with lncRNAs. ...
Introducing Beacon Biosignals: a neurotechnology company founded to develop machine learning-enabled EEG neurobiomarkers and accelerate precision medicine for any disease state affecting the brain Founded by MD/PhDs and engineers from Harvard and MIT, Beacon is propelled by the vision of a computing platform designed to scale the interrogation of large brain datasets with ...
The effectiveness of kinases as targets for other diseases, including neurological disorders, inflammation and metabolic diseases, is also being tested. ...
Abstract—The current study aims to evaluate the performance of the Circadia Sleep Analysis Algorithm, which - in combination with the non-contact and minimally invasive Circadia bedside monitor - allows for long-term sleep assessment and continuous evaluation of sleep therapy outcomes. The Circadia Contactless Respiratory Monitor was initially used to record 17 nights of sleep data from 9 ...
The microbiome has been shown to play roles in many different disease processes and is implicated in many more, from infectious and gastrointestinal diseases to autoimmune and neurological disorders. ...
1 billion people around the world are currently suffering from neurological disorders, and the number is growing by the day. The COVID-19 pandemic has had a significant negative impact on the healthcare system’s ability to effectively diagnose and treat these individuals. ...
Introduction Reactive astrocytes are associated with most forms of neurological disorders, ranging from acute injury to degeneration (1), and play diverse roles in these disease states. ...
Alcyone Lifesciences is a medical technology company based out of Lowell, MA, which specializes in central nervous system (CNS) drug delivery platforms for targeted infusions of the brain or spinal cord. Their Thecaflex DRx System was recently awarded Breakthrough Device designation by the FDA, for spinal infusion of therapeutic medications. Medgadget had the opportunity to speak with Alcyone ...