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Neuropathy Articles & Analysis

19 articles found

Unveiling the Intricacies of DNM1L: Function, Associated Diseases, and Inheritance Patterns

Unveiling the Intricacies of DNM1L: Function, Associated Diseases, and Inheritance Patterns

One such disease is Charcot-Marie-Tooth disease type 2A (CMT2A), a hereditary peripheral neuropathy characterized by progressive muscle weakness and sensory loss. ...

ByCreative BioMart


What causes heart failure with preserved ejection fraction (HFpEF)?

What causes heart failure with preserved ejection fraction (HFpEF)?

Hyperglycemia and insulin resistance can promote autonomic neuropathy, contributing to cardiac stiffness, hypertrophy, and fibrosis. [41] Sex Differences The higher occurrence of HFpEF in women suggests that sex-dependent mechanisms may be involved in HFpEF pathogenesis (Dunlay et al., 2017).[41] In general, women tend to show more concentric LV remodeling, with smaller LV ...

ByUltromics Limited


Baroreflex Activation Therapy: A Novel Approach for HFrEF Patients

Baroreflex Activation Therapy: A Novel Approach for HFrEF Patients

Patients are contraindicated if they have been assessed to have bilateral carotid bifurcations located above the level of the mandible, baroreflex failure or autonomic neuropathy, uncontrolled symptomatic cardiac bradyarrhythmias, carotid atherosclerosis that is determined by ultrasound or angiographic evaluation greater than 50%, ulcerative plaques in the carotid artery as ...

ByCVRx


Huateng Pharma Develops Intermediates of Carfilzomib For Multiple Myeloma

Huateng Pharma Develops Intermediates of Carfilzomib For Multiple Myeloma

(2) Safety and Tolerability Compared with bortezomib, carfilzomib had less peripheral neuropathy. In RRMM patients, the rate of grade 3 peripheral neuropathy was 1.3%, but no patients had grade 4 events, and only 1% of patients required dose adjustment or Withdrawal. ...

ByHunan Huateng Pharmaceutical Co. Ltd.


Diabetic Foot Ulcer - Case Study

Diabetic Foot Ulcer - Case Study

Insulin dependent diabetic, peripheral neuropathy, hypertension, renal failure on hemodialysis; history of chronic foot ...

ByETS Wound Care


Diabetic Foot Ulcer - Case Study

Diabetic Foot Ulcer - Case Study

Non-insulin dependent diabetes, venous insufficiency, peripheral neuropathy, HTN, CHF, COPD, ...

ByETS Wound Care


Deep Tissue Injury (Traumatic) - Case Study

Deep Tissue Injury (Traumatic) - Case Study

Subject: 68/female. Diabetes, peripheral neuropathy, and venous insufficiency. Necrotic tissue was treated with moistened MIRRAGENâ„¢ advanced wound matrix for 2 days to soften and loosen necrotic tissue for easy ...

ByETS Wound Care


Understanding and Treating Diabetic Neuropathy

Understanding and Treating Diabetic Neuropathy

What is diabetic neuropathy? The most common complication of diabetes is neuropathy, which is nerve damagecaused by high blood sugar. Most neuropathy affects the legs, hands and feet and usually presents as numbness, pain or tingling. ...

ByBioWave Corporation


Treating Peripheral Neuropathy Holistically

Treating Peripheral Neuropathy Holistically

For example, if a patient comes in with a sharp, jabbing pain in his hand - a symptom of peripheral neuropathy - a holistic treatment plan may not only include pain relief medicine but also address underlying causes of pain. ...

ByBioWave Corporation


Treatment of a Pressure Ulcer using CDO Therapy - Case study

Treatment of a Pressure Ulcer using CDO Therapy - Case study

Christine Salcher, DPM Sherman, Texas and Amyee McAlister, Healthline Patient: 50-year-old Caucasian female with a pressure ulcer that has progressively gotten larger, deeper, more malodorous, fibrotic, and necrotic Comorbidities: Diabetes, diabetic retinopathy & peripheral neuropathy Age of Wound: 90 days Days on Service: 55 days Outcome: Goals met. ...

ByEO2 Concepts


Diabetic Burnout: What is it & how can we help ourselves?

Diabetic Burnout: What is it & how can we help ourselves?

Severely high blood sugar levels and long-term burnout that leads to long-term high blood sugars can increase your risk for many of the diabetes complications you’ve been warned about, such as neuropathy, retinopathy, nephropathy, and slow wound healing. Bottom line, diabetes is a chronic and demanding disease. ...

ByEO2 Concepts


Beyond Insulin: Immunotherapy for Type 1 Diabetes-PI   

Beyond Insulin: Immunotherapy for Type 1 Diabetes-PI  

However, over time, many patients still develop complications, including cardiovascular disease, retinopathy, neuropathy, and nephropathy. T1D goes through several stages before the onset and the clinical diagnosis is obtained. ...

ByCreative Biolabs


Three generations of ADC Nearly a decade of development-PIII   

Three generations of ADC Nearly a decade of development-PIII  

However, Adcetris, when used alone, caused potentially severe peripheral neuropathy, neutropenia, and thrombocytopenia, all of which are typical side effects of antiplatelet drugs. ...

ByCreative Biolabs


Why You Have Numb Fingers While Sleeping

Why You Have Numb Fingers While Sleeping

These reasons are given in order from the most to least common: Sleeping in a bad position Carpal tunnel syndrome Cubital tunnel syndrome Peripheral neuropathy (diabetes and alcohol abuse) Cervical Spondylosis Raynaud's disease Vascular diseases Stroke Multiple sclerosis Medication Side Effects (Chemotherapy) Vitamin B12 Deficiency Numb finger numbness due to ...

ByCarpal Pain Solutions. LLC


What is a Posturography?

What is a Posturography?

Reid et al. [6] also used posturography to assess the incidence of large-fiber peripheral neuropathy by comparing the results with conventional electromyography (EMG) results. ...

BySensing Future Technologies


Temple research finds that tweaking CBD may help it curb pain and opioid use in mice

Temple research finds that tweaking CBD may help it curb pain and opioid use in mice

Doylestown-based Neuropathix is running safety tests required to start clinical trials in humans. The compound may help with neuropathy, a severe type of chronic pain associated with cancer treatment. ...

ByNeuropathix, Inc.


Philly Pharmacologists are Developing a Promising Pain-Relieving CBD Analog Drug

Philly Pharmacologists are Developing a Promising Pain-Relieving CBD Analog Drug

When tested on mice, their compound, KLS-13019, demonstrated both prevention and reversal of chemotherapy-induced peripheral neuropathy (CIPN), a common side effect of certain cancer treatments that damage peripheral nerves, which carry sensory information to the arms, legs, and brain. ...

ByNeuropathix, Inc.


CBD: Perils, Promise and Development for Neuropathic Pain

CBD: Perils, Promise and Development for Neuropathic Pain

Kannalife is developing proprietary CBD and CBD-like molecules for neurodegenerative disorders, including chemotherapy-induced peripheral neuropathy (CIPN). This is a chronic nerve pain caused by the toxic aspects of chemotherapy drugs. ...

ByNeuropathix, Inc.


HBOT for Complementary Therapy

HBOT for Complementary Therapy

It can be used in conjunction with other auxiliary therapies to treats medical conditions that include: Skin and soft tissues diseases: Thermal burns, chemical burns, radiation burns Frostbite Scalds Skin infections (erysipelas, pyoderma, actinomycosis, aspergillosis, Gram negative bacteria infections, nosocomial infections) Dry skin Cutaneous ulceration (caused by vein insufficiency , ...

ByOXYHELP INDUSTRY

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