Pancreatic Cells Articles & Analysis
13 articles found
Chemotherapy APIs function by disrupting cell division processes, which inhibits the rapid replication of cancer cells. ...
These oral antidiabetic medications mainly work by increasing insulin sensitivity, slowing down the metabolism of carbohydrates in the small intestine, repairing and improving the function of pancreatic β-cells, and promoting insulin secretion to achieve blood glucose reduction. ...
So far, anti-mesothelin antibody-drug conjugates have been successfully used to treat mesothelin-expressing solid tumors, including ovarian cancer, pancreatic cancer, and malignant mesothelioma; and mesothelin targets chimeric antigen receptor (CAR) T cell therapy also showed significant antitumor effects. ...
Mesothelin or MPF supplementation stimulates lung cancer growth in MSLN knockout mice, which verifies the role of mesothelin in tumor cell adhesion, migration, and metastasis. Role of mesothelin in cancer and signaling Mesothelin is expressed in many solid tumors, most commonly in mesothelioma, epithelial ovarian, and pancreatic cancers, as well as in lung and ...
Further studies of other solid tumor types, including pancreatic, ovarian, and lung cell lines, showed the same results: the resistance to CAR-T cell therapy stems from the loss of interferon pathway genes. "We found that CAR-T cells did not bind to glioblastoma cells that lack interferon signaling," Larson ...
Studies have shown that lncRNAs are quite complex in function and play an important role in various biological processes such as development, differentiation, proliferation, metastasis, apoptosis, stem cell pluripotency, and DNA damage. Therefore, those non-coding fragments in human genes are also vital and not the so-called "transcriptional noise". ...
Abstract Transplantation of pancreatic islets has been shown to be effective, in some patients, for the long-term treatment of type 1 diabetes. ...
Glycosylation regulates a range of physiopathological processes, including cell-cell adhesion, cell-matrix interactions, epithelial-mesenchymal transition, tumor proliferation, invasion, metastasis, and angiogenesis. ...
Pancreatic cancer is at an advanced stage when diagnosed when cancer cells have spread and are hard to control. ...
The results provide new insights into how pancreatic cancer cells grow and point to new possibilities for the treatment of this cancer. ...
Killer T-Cells are responsible for destroying bacteria and viruses in healthy people, but for those with type 1 diabetes they attack beta cells. ...
The proton beam was investigated for cancer cell therapy in the pancreas. Neon ion interaction profiles were compared with the result of the proton beam, which was investigated for nanoscale ion beam interactions. ...
It is required early for the formation of the undifferentiated tubular epithelium of the nascent pancreatic rudiment and then becomes restricted to the differentiating acinar cells, where it directs the transcriptional activation of the secretory digestive enzyme genes. ...