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Physiological Role Articles & Analysis

4 articles found

Exploring the BALB/C Mouse Kidney FFPE Block: A Vital Tool in Biomedical Research

Exploring the BALB/C Mouse Kidney FFPE Block: A Vital Tool in Biomedical Research

Among the various tissues studied, the kidney holds significant importance due to its complex structure and multifaceted role in physiological functions. A formalin-fixed paraffin-embedded (FFPE) block of the BALB/C mouse kidney serves as an essential resource for researchers, allowing for detailed histopathological and molecular examinations. ...

ByCreative Bioarray


Understanding Nuclear Receptor Screening: Unveiling the Potential of Drug Discovery

Understanding Nuclear Receptor Screening: Unveiling the Potential of Drug Discovery

Nuclear receptors are a class of proteins that play a vital role in cellular communication, gene expression, and overall homeostasis within the body. They act as transcription factors, responding to various stimuli, including hormones, nutrients, and even environmental agents. Due to their crucial roles in physiological and pathological ...

ByCreative Biogene


NEBS and PIEZO2: Guardians of the Respiratory Galaxy

NEBS and PIEZO2: Guardians of the Respiratory Galaxy

In a recent Nature publication by Schappe,M (2024), researchers have revealed a fascinating aspect of respiratory physiology: the role of sensory neurons in guarding against airway obstruction and orchestrating crucial reflexes to maintain respiratory function. ...

BySCIREQ - an emka TECHNOLOGIES Company


Physiological role for phosphatidic acid in the translocation of the novel protein kinase c apl ii in aplysia neurons

Physiological role for phosphatidic acid in the translocation of the novel protein kinase c apl ii in aplysia neurons

In Aplysia californica, the serotonin-mediated translocation of protein kinase C (PKC) Apl II to neuronal membranes is important for synaptic plasticity. The orthologue of PKC Apl II, PKC, has been reported to require phosphatidic acid (PA) in conjunction with diacylglycerol (DAG) for translocation. We find that PKC Apl II can be synergistically translocated to membranes by the combination of DAG ...

ByAmerican Society for Microbiology (ASM)

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