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Prostate Specific Membrane Antigen Articles & Analysis

11 articles found

Peptide Vaccine Design

Peptide Vaccine Design

Peptide vaccines are increasingly seen as an economically efficient and safe approach to circumvent this issue.Peptide Vaccine DevelopmentThe vaccine development process is a challenging multi-step process: Antigen selection→Epitope selection→Adjuvant selection→Peptide vaccine synthesis→Immunization study→In vitro evaluation→Clinical trial.The development of peptide vaccines ...

ByCreative Peptides


FDA Approved Peptide Drugs in the First Half of 2023

FDA Approved Peptide Drugs in the First Half of 2023

Mammalian cells do not express β-1-3-glucan synthase, therefore, the action of rezafungin is specific to fungi. 3. Posluma (flotufolastat F 18) Posluma (flotufolastat F 18) is an 18F-labeled ligand and an imaging agent for the detection and localization of prostate cancer in PET (positron emission tomography). Posluma contains an imaging agent (18F) whose ...

ByCreative Peptides


B7-H3: Broad Prospects of Emerging Tumor Immunotherapy Targets

B7-H3: Broad Prospects of Emerging Tumor Immunotherapy Targets

Recently, in the renowned academic journal Nature Medicine, the Kimmel Cancer Center at Johns Hopkins University published Phase 2 clinical results regarding enoblituzumab, a monoclonal antibody targeting B7-H3, for the treatment of prostate cancer. The results demonstrate that enoblituzumab can successfully induce the body's anti-cancer activity, showing favorable therapeutic ...

ByBeta Lifescience


Enzymes for Disease Diagnosis: An Overview

Enzymes for Disease Diagnosis: An Overview

Enzymes are protein molecules that catalyze chemical reactions in living organisms. They are involved in many metabolic processes and play a critical role in maintaining the health of the body. In recent years, enzymes have been widely used in disease diagnosis, providing a quick and accurate way to detect and monitor diseases. Enzymes for disease diagnosis can be divided into two categories: ...

ByCreative Enzymes


Enzyme for Diagnosis: Revolutionizing Medical Diagnostics

Enzyme for Diagnosis: Revolutionizing Medical Diagnostics

Enzymes are biological catalysts that accelerate chemical reactions in living organisms. In recent years, enzymes have been increasingly utilized in medical diagnostics, leading to significant advancements in disease detection and management. Enzyme-based diagnostic tools have revolutionized the healthcare industry, offering numerous benefits such as increased accuracy, sensitivity, and speed. ...

ByCreative Enzymes


Antibody-Drug Conjugates For The Treatment of Prostate Cancer

Antibody-Drug Conjugates For The Treatment of Prostate Cancer

STEAP1, TROP2, PSMA, CD46, and B7-H3 are currently being looked at as optimal antigens, which have been shown to be targeted by ADCs. 1. ADC For The Treatment of PCa PSMA-based ADCs PSMA (prostate-specific membrane antigen) is a cell membrane protein specifically expressed ...

ByHunan Huateng Pharmaceutical Co. Ltd.


Nanostics Re-Opens ClarityDX Prostate Clinical Study with New US Recruitment Site

Nanostics Re-Opens ClarityDX Prostate Clinical Study with New US Recruitment Site

Summary Nanostics' clinical validation study for ClarityDX Prostate, a liquid biopsy test for the early diagnosis of clinically significant prostate cancer, re-opens recruitment after lifting of COVID-19 research restrictions A top-ranked research institute in the Northeast US will now partner with Nanostics' by recruiting patients for the clinical validation study This partnership will ...

ByNanostics Inc.


Validation of ClarityDX Prostate as a Reflex Test to Refine Prediction of Clinically Significant Prostate Cancer: ClinicalTrials.gov ID: NCT03957252

Validation of ClarityDX Prostate as a Reflex Test to Refine Prediction of Clinically Significant Prostate Cancer: ClinicalTrials.gov ID: NCT03957252

Summary This study is designed to determine the accuracy of the blood test ClarityDX Prostate to predict the results of prostate biopsies in men who have PSA (Prostate Specific Antigen) greater than 3 and no higher than 10 ...

ByNanostics Inc.


Bio-tech firm recruiting Yukon men for trial, Prostate cancer group says it could save lives

Bio-tech firm recruiting Yukon men for trial, Prostate cancer group says it could save lives

The Yukon chapter of Ride For Dad says a new blood test developed by an Alberta-based company could save the lives of men at risk of prostate cancer. (iStock/Getty Images) A bio-technology company based in Alberta is testing a new process that could result in fewer Yukon men travelling out of territory for prostate cancer biopsies. Private research company Nanostics Inc. and the University of ...

ByNanostics Inc.


Cost-Effectiveness of Urinary Biomarker Panel in Prostate Cancer Risk Assessment

Cost-Effectiveness of Urinary Biomarker Panel in Prostate Cancer Risk Assessment

Abstract Purpose: SelectMDx (MDxHealth®) is a panel of urinary biomarkers used in conjunction with traditional risk factors to individualize risk prediction for clinically significant prostate cancer. In this study we sought to characterize the effectiveness of SelectMDx in a population of American men with elevated prostate specific antigen. Materials and methods: We developed a ...

ByMDxHealth


Design and analysis of nanowire sensor array for prostate cancer detection

Design and analysis of nanowire sensor array for prostate cancer detection

Prostate cancer is one of the major cancer affecting men in India. After lung cancer, prostate cancer has caused large number of deaths in India. Nanowire is the biosensor used for detection of cancer. In this paper, we present a design of nanowire array sensor for prostate cancer detection. A sensor array of 8 × 8 elements is designed to capture the PSA present in the blood that helps in ...

ByInderscience Publishers

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