Protective Immunity Articles & Analysis
12 articles found
FcRn is widely involved in various biological and immune processes in the body, playing roles in immune protection, maintaining the stability of IgG, transmembrane transport, and mother-infant transmission. ...
Antibodies are an essential part of our immune system, capable of recognizing foreign molecules (antigens) and helping to eliminate them. ...
Drug antibody testing is a laboratory testing method specifically designed to evaluate the immune response of the human body to certain drugs. This test is commonly used to monitor a patient's immune response to biological agents or other drugs, especially in the treatment of chronic diseases such as autoimmune diseases, certain cancers, and inflammatory ...
Adjuvants can help antigens induce long-term effective specific immune responses in vivo, leading to higher vaccine efficacy and prolonged protection from immune responses. ...
Here, using a genetic timestamping system in mice, we show that persistent PCs accrue in bone marrow at an approximately constant rate of one cell per hour over a period spanning several weeks after a single immunization with a model antigen. Affinity-based selection was evident in persisting PCs, reflecting a relative and dynamic rather than absolute affinity threshold as ...
Attenuated vaccines have become one of the important development directions due to their potential advantages in terms of immune effects, for example, attenuated influenza vaccines can be inoculated by intranasal spray that is simpler, economical, painless, and consistent with the natural route of infection; they can retain the natural structure of all or most antigens of the ...
“The M2SR vaccine candidate is designed to induce a broad, multi-effector immune response, and this study demonstrated that subjects with vaccine-induced neutralizing antibodies were protected against infection and illness following challenge with an antigenically drifted virus. ...
Every year, millions of people are vaccinated to strengthen their immunity and protect themselves from infectious diseases. According to the regulations of the World Health Organization (WHO), vaccination is an approved tool for dealing with deadly contagious diseases that kill 3 million people worldwide. ...
ByAKCP
VC2 vaccination in mice produced superior protection and morbidity control in comparison to its parental strain HSV-1 (F). ...
Individuals living in areas of high P. falciparum ransmission acquire protective immunity to severe malaria during early childhood after only a few symptomatic infections yet remain susceptible to uncomplicated disease and asymptomatic infection into adulthood (65). Thus, sterile immunity that prevents nfection may never develop, but ...
Individuals living in areas with stable transmission of Plasmodium falciparum parasites develop substantial protective immunity to the disease during childhood. Because of naturally acquired immunity, which appears mainly to target parasite-encoded Variable Surface Antigens (VSA) on the Infected Erythrocytes (IE), severe and life-threatening ...
These results indicate that our purified cell culture-derived bivalent vaccine is safe, well-tolerated and capable of inducing a protective immunity.Keywords: haemorrhagic fever with renal syndrome, HFRS, inactivated bivalent vaccine, cell culture based vaccine, immunogenicity, human clinical trials, safety, tolerance, China, neutralising antibody titers, ...