Protein Expression Articles & Analysis: Older
74 articles found
The principle is to clone one or several antigen genes of a pathogen into host cells, causing them to express the corresponding antigen protein. These proteins are then extracted for use in the vaccine. ...
Protein-free medium Protein-free media do not contain any protein, only non-protein components. Using protein-free media improves cell growth and protein expression compared to serum-supplemented media, and facilitates downstream purification of any expressed ...
By combining surface marker profiles with indexes and transcriptomes, the authors now have a map of each cell type that can be used for later identification. They also measured the expression of an additional 352 surface markers that were not used in the original isolation protocol and that might better differentiate cells in the future. Indexed sorting data allowed each ...
One promising strategy is to deliver genes that express tumor suppressor proteins or anticancer agents into cancer cells to induce cell death or inhibit their proliferation. ...
Differentially expressed proteins refer to proteins that show significant changes in their expression levels in different biological samples or under different treatment conditions. ...
The immune system plays a crucial role in protecting the body from harmful pathogens and foreign invaders. Immune receptors, which are protein molecules expressed on the membrane of immune cells, play a key role in regulating immune responses. ...
Protein-Protein Interaction Sequencing (PPI-Seq) is an emerging technology. Based on high-throughput sequencing, it allows researchers to explore protein interactions at the whole genome level.Technical PrinciplesThe basic principle of Protein-Protein Interaction Sequencing is to use the yeast two-hybrid system ...
Mass Cytometry (CyTOF): This technique allows for the simultaneous measurement of dozens of protein markers in individual cells. By furnishing a detailed protein expression profile, CyTOF helps to understand how different cell populations within the tumor interact and respond to therapies. ...
Collagen, as one of the most abundant proteins in the human body, plays a key role in maintaining the integrity and function of tissue structures. ...
Gene knockout is a procedure that inactivates the function of a specific gene, making it unable to express normally, through genetic engineering techniques. This operation can help us understand the function and role of this gene in an organism. ...
Protein-Protein Interaction databases primarily record experimentally validated protein interaction data. Here are some key Protein-Protein Interaction databases:BioGRID(Biological General Repository for Interaction Datasets)BioGRID is a database focused on biological molecular interactions, including ...
Recombinant collagen is a type of collagen protein expressed in microorganisms, animal cells, or plants through genetic engineering technology. ...
Sequence AlignmentAlign with known protein sequences to identify homologous proteins, which helps to infer protein function and evolutionary relationships.2. ...
ComprehensivenessIt can detect more proteins and peptides in the sample, providing more comprehensive proteome coverage.2. ...
The retained intron can contain important regulatory elements, such as protein-binding sites or microRNA target sites, which can influence gene expression or protein function. ...
There are unlimited uses for point mutation cell lines at pre-defined loci, including functional assays, drug screening, FACS screening of membrane proteins, gene expression studies, gene therapy and antibody immunization boosting research. ...
Creative Biogene has established various plant-based protein expression systems to provide recombinant protein production service for global clients. Using our state-of-art platform, we offer a complete service that begins from a specific gene to the purified protein, as well as different options for protein ...
Creative Bioarray provides customers with comprehensive stem cell assay development and screening service, such as: cell viability assay, proliferation, apoptosis, ion transport, pathway signaling, gene expression, protein expression, and post-translational modifications. Advantages of Creative Bioarray Service: Worldwide accepted and advanced ...
Protein fusion is a genetic recombination technique in which the DNA of an inactive peptide or protein chain segment to be grafted is recombined with the DNA of a drug and expressed together by engineered cells; no specialized grafting operations are required. ...
In recent years, various nucleic acid-based therapies (NBT) have emerged as effective and specific activators of endogenous gene expression. Unlike gene therapy approaches supplementing gene expression, RNA-targeted therapy enhances protein production by selectively modulating cellular mechanisms mediated by endogenous RNA, such as transcription, ...