Pulmonary Disease Articles & Analysis: Older
21 articles found
Precision-Cut Lung Slices (PCLS) have emerged as a innovative ex vivo model that allows researchers to explore deep into lung physiology, disease mechanisms, and pharmacological responses. By offering a unique combination of biological complexity and controlled experimental conditions, PCLS serve as a critical bridge between the limitations of traditional in vitro cell cultures and the ...
Elastase in Pathological Conditions One of the most well-studied conditions involving elastase is emphysema, a form of chronic obstructive pulmonary disease (COPD). In emphysema, excessive activity of neutrophil elastase results in the degradation of elastin in the lung's alveolar walls, leading to impaired lung function and reduced elasticity. ...
Evaluating the stress related effects of various restraint methods in rodents Any restraining device used in an inhalation exposure set-up will be, by definition, restricting the subject’s ability to move. For nose-only inhalation set-ups, typical restraints are rigid, fully enclosed and include a metal or acrylic plunger forcing the subject forward and preventing the subject from ...
The field of medical science has long utilized disease models, which are systems simulating the progression and expression of a disease, to better understand various illnesses. ...
The field of medical science has long utilized disease models, which are systems simulating the progression and expression of a disease, to better understand various illnesses. ...
Cytokine Dysregulation in Systemic Immune Diseases The perturbation of immune tolerance leads to disruption in cytokine homeostasis. ...
Cardiovascular safety liabilities caused 52.3 % of 44 marketed data from 1980 to 2011, and cardiovascular disease remains the leading cause of death globally, yet only 8.7% of cardiovascular drugs successfully pass clinical trials. ...
HFpEF patients are likely to have a high prevalence of cardiovascular and non-cardiovascular comorbidities, such as obesity, metabolic syndrome, diabetes mellitus type 2, salt-sensitive hypertension, atrial fibrillation (AF), chronic obstructive pulmonary disease, anaemia, and renal dysfunction.[6.7,8] As life expectancy and comorbidity rates rise, the ...
With regard to ischaemic aetiology, HFmrEF more resembles HFrEF, but HFmrEF has a higher frequency of underlying coronary artery disease (CAD) and a better overall prognosis. Comorbidities While there are differences between the cellular and structural comorbidities of HFpEF and HFrEF, there are some similarities. ...
Dental Problems Linked To Heart Disease and Diabetes Over the last ten years there has been a growing body of evidence linking periodontal disease and systemic diseases. ...
By now, you are likely aware of many of the well-established risks associated with smoking cigarettes, such as cancer, asthma, chronic obstructive pulmonary disease (COPD), diabetes, cardiovascular disease, and stroke. ...
Clinical studies have documented numerous effective benefits and support for people facing a variety of health challenges, including: a) Asthma b) Atherosclerosis c) Autoimmune disease d) Bronchitis e) Cancer f) Chronic obstructive pulmonary disease ... Although the benefits of proteases for these and ...
The Non-Intrusive LuCED Test for Detection of Early-Stage Lung Cancer: A Subgroup Analysis for Chronic Obstructive Pulmonary Disease (COPD) Introduction VisionGate’s LuCED® test for lung cancer measures 934 features in each cell imaged in 3D by the Cell- CT™. ...
After a lightning round of proposals and reviews, an international team of scientists led by Dr. Camillo Ricordi was granted immediate FDA authorization for a 24-patient clinical trial to test the safety and exploratory efficacy of umbilical cord-derived mesenchymal stem cells (UC-MSCs) to block the life-threatening lung inflammation that accompanies severe cases of COVID-19. The therapy uses ...
General clinical characteristics of 25 dead patients: all of them have basic diseases, including 16 cases of hypertension, 10 cases of diabetes, 8 cases of heart disease, 5 cases of kidney disease, 4 cases of cerebral infarction, 2 cases of chronic obstructive pulmonary disease, 2 cases of malignant tumor, 1 ...
The medical device registration certificate issued by the Municipal Drug Administration is officially on the market and will soon bring good news to must patients with chronic obstructive pulmonary disease. Chronology November 2015, Respiratory neuromuscular stimulator was officially launched. ...
Among the exclusion criteria were chronic obstructive pulmonary disease, renal failure, bleeding disorders, pulmonary hypertension, antiarrhythmic drugs, and antibiotics. ...
This case study discusses hospital readmissions and provides healthcare professionals with recommended medical algorithms in the form of scores, models, and calculators that can aid in reducing readmissions, especially when related to antibiotic resistant microbiological pathogens. When health analytics, such as the CDC antibiotic resistance program and other algorithms are integrated into ...
The intractable problem of tuberculosis (TB) control despite advances in chemotherapy requires additional research effort to unravel the pertinent factors that make the disease preponderant in developing countries. The present study examined the pattern of TB morbidity in Lagos metropolis with the aim of identifying the explanatory factors. Data on reported cases of ...
In pediatric population the use of IS for the prevention of ARTIs needs to be limited to children with high susceptibility to ARTIs or overexposed children, while in adults it must be indicated for patients with Chronic Obstructive Pulmonary Diseases (COPD) at high risk of exacerbation.Keywords: immunostimulants, action mechanisms, acute respiratory tract ...