Refine by
Therapeutic Benefit Articles & Analysis
15 articles found
Idiopathic pulmonary fibrosis (IPF) is a devasting lung disease characterized by progressive scarring of lung tissue. As fibrosis develops, patients experience worsening shortness of breath, reduced lung capacity and ultimately respiratory failure. Current therapies for IPF rely on oral administration of pirfenidone and nintedanib, two FDA-approved drugs that slow disease progression. While ...
It transforms liquid solutions into stable, free-flowing amorphous powders with precise particle sizes that can dramatically improve a drug’s shelf-life, bioavailability, taste, and therapeutic effectiveness. This simple yet powerful technology can even be used to develop complex treatments like RNA therapeutics, inhalable medications, and nutraceuticals. ...
ByBUCHI
In the context of cancer, parthanatos has garnered attention as another mechanism that can be targeted for therapeutic benefit. Cancer cells often exhibit variations in their apoptotic pathways, making them resistant to conventional treatments that rely on apoptosis. ...
It has gained considerable interest in both the medical and wellness communities for its potential therapeutic benefits, particularly in promoting pain relief, reducing inflammation, and aiding tissue healing. ...
Curcumin, a natural compound found in turmeric, has gained attention for its potential health benefits, including anti-inflammatory and antioxidant properties. It has been studied for its ability to support joint health, improve brain function, and reduce the risk of various diseases. ...
Peptidomimetics can mimic the structure and function of peptides, making them a valuable tool for the study of natural processes and the development of new therapeutic strategies.Structural ModificationsPeptidomimetics are generally structurally modified to enhance their stability, binding affinity, and selectivity to increase the stability of the target protein or receptor. ...
In recent years, alkaloids have gained significant attention in the field of modern medicine due to their potential therapeutic benefits. In this article, Alfa Chemistry will take stock of some common alkaloids used as medicines. ...
Finally, sophisticated algorithms and computational models rank and prioritize the compounds based on predicted binding affinity and therapeutic activity. Benefits of Virtual Screening: Accelerated Drug Discovery: Virtual screening dramatically reduces the time and resources required to identify potential drug candidates. ...
Weight-Bearing Activity: Weight-bearing is a technique that involves loading muscles and joints for a therapeutic benefit. In the case of subluxation of the shoulder, carefully applied weight-bearing may promote joint approximation and compression of the head of the humerus into the shoulder capsule. ...
However, the full potential of SC delivery has been held back. Availability of SC Therapeutics – To date, the number of therapeutics marketed for SC administration is limited despite the advantages SC has over IV administration. ...
Progenza™ and Sygenus have great therapeutic potential which can positively impact the quality of life of patients suffering from osteoarthritis and other inflammatory conditions. I am most excited to see the progression of our products to clinical trials and ultimately to the market, as I have witnessed in our preclinical trials their potential to be life-changing and ...
Recent Phase I and II studies of cancer vaccines, tested in a variety of malignancies, have suggested that ELISpot may be a useful biomarker assay to predict clinical benefit after therapeutic immune modulation. This article will discuss the most common applications of ELISpot, overview the efforts that have been undertaken to standardize the assay and apply the ...
Previous studies suggested that L. rhamnosusshowed the therapeutic effects for AD.42–44 Especially, L. rhamnosus GG is widely reported strain for AD prevention and treatment.43,44 Therefore, in this study, we used L. rhamnosus KBL365, isolated from healthy Korean feces, to confirm the effects of L. paracasei on AD. Although some L. rhamnosus strains suppress the progression ...
Despite widespread clinical use, its therapeutic mechanisms are unknown. Here, we developed a mouse model of subthalamic nucleus (STN) DBS for PD, to permit investigation using cell type–specific tools available in mice. ...
An extensive specialist market also exists for fish oils in dietary supplements. Traditionally, benefits have been conferred by their high vitamin D content in the prevention and cure of rickets in children. Therapeutic benefits in the treatment of cardiovascular, arthritic and dermatological disease have also been identified. ...