Vaccine Efficacy Articles & Analysis
26 articles found
Encapsulating anticancer drugs within its lipid bilayer improves drug accumulation in target tissues while reducing toxicity to healthy cells.Immunomodulatory TherapyFunctionalized DSPE-PEG-Mannose nanoparticles can modulate immune responses by interacting with mannose receptors on immune cells, contributing to novel treatments for immune-related disorders.Cell Recognition and SeparationBy ...
Vaccines have been essential in disease prevention, and the requirements for vaccine quality continue to increase. The application of advanced separation and purification technologies during the preparation of traditional and new vaccines is an effective means to improve vaccine efficacy and reduce side effects. ...
The advent of mRNA vaccines has revolutionized the field of immunization, offering a rapid and adaptable response to emerging infectious diseases. Central to the production of these vaccines are enzymes, which play crucial roles in the synthesis and modification of mRNA molecules. This article delves into the pivotal functions of enzymes in mRNA ...
Vaccines have been essential in disease prevention, and the requirements for vaccine quality continue to increase. The application of advanced separation and purification technologies during the preparation of traditional and new vaccines is an effective means to improve vaccine efficacy and reduce side effects. ...
While mRNA vaccines have shown remarkable efficacy in clinical trials and real-world use, researchers are constantly looking for ways to enhance their effectiveness and duration of protection. ...
In a significant stride towards eradicating a debilitating disease, a new polio vaccine has achieved WHO prequalification. This development represents a crucial milestone in global health, where effective vaccination remains our strongest defence. ...
The breakthrough: halving death rates with vaccines When it comes to infectious diseases, few advancements have been as significant and hopeful as the development and deployment of an effective vaccine, and the case for Ebola is no different. ...
Adjuvants can help antigens induce long-term effective specific immune responses in vivo, leading to higher vaccine efficacy and prolonged protection from immune responses. Adjuvants can also reduce the amount of antigen used, the cost of production and the number of immunizations. ...
Quality containers ensure that vaccines remain at the required temperature, preventing any degradation in their efficacy. ...
This article explores the intricate and indispensable role that raw enzymes play in the manufacturing of mRNA vaccines, delving deep into their significance and impact on vaccine production. ...
Vaccine excipients play a crucial role in the development and manufacturing of vaccines. These are substances added to the vaccine formulation to enhance its stability, efficacy, and safety. Vaccine excipients can include adjuvants, stabilizers, preservatives, and additives. ...
Therefore, MosquirixTM requires a storage temperature between 2°C and 8°C, failure of which may damage the antigen and/or adjuvant and reduce the vaccine’s efficacy or safety. The second one (R21/Matrix MTM) is made up of fusion proteins and the Matrix MTM adjuvant which stimulates the recipient’s immune response toward the ...
MADISON, Wis., Sept. 7, 2022 /PRNewswire/ — FluGen, Inc., a clinical-stage vaccine company transforming vaccine efficacy in infectious respiratory diseases, today announced the completion of enrollment of the first cohort in an age de-escalation clinical trial of M2SR (M2 Deficient Single Replication) live virus vaccine, ...
The study will evaluate the safety, tolerability, and immunological response to FluGen’s investigational supra-seasonal, live, single-replication, intranasal M2SR influenza (flu) vaccine, and high dose inactivated vaccine (IIV). There is a demonstrated unmet need for improved flu vaccine options, as current injectable ...
Among the threats topping that list were another global influenza pandemic, Ebola and other high threat pathogens, and vaccine hesitancy. The WHO describes vaccine hesitancy as the delay in acceptance or refusal of vaccines, despite their level of availability. ...
Data published in the Journal of Infectious Diseases demonstrate that M2SR can protect against a multi-seasonal, seven-year drifted influenza strain – MADISON, Wis., Aug. 2, 2021 /PRNewswire/ — FluGen, Inc., a clinical-stage vaccine company transforming vaccine efficacy in infectious respiratory diseases, today announced the ...
If you are fully vaccinated, should you be worried about the impact of COVID-19 variants? No, in fact vaccines have been shown to be highly effective at preventing hospitalizations and deaths from these SARS-CoV-2 variants. While the infamous Delta variant has now been detected in 98 countries and all 50 states, 99% of all COVID-19 deaths and hospitalization cases are unvaccinated, according to ...
Study is the Company’s first trial evaluating ability of M2SR and the current licensed standard of care to protect against drifted virus strains, and its second study in older adults, a population most vulnerable to mortality from flu – Safety and immunogenicity study expected to begin in Q2 2022 – MADISON, Wis., July 1, 2021 /PRNewswire/ — FluGen, Inc., a clinical-stage ...
Study will measure immune responses to matched and drifted virus strains in older adults, a population that is most vulnerable to mortality from flu – Topline data expected in 1H 2022 – MADISON, Wis., May 25, 2021 /PRNewswire/ — FluGen, Inc., a clinical-stage vaccine company transforming vaccine efficacy in infectious ...
Childhood vaccinations provide immunity to children against serious infectious diseases before they are exposed to them to prevent illness. Many childhood diseases, such as smallpox and polio, have been almost completely eradicated as a result of widespread, standardized childhood vaccination programs. Some vaccinations, such as those for highly ...