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SIG-005: Novel Encapsulated Non-Viral Cell-Based Therapy for MPS-1

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Jun. 30, 2021- By: Marissa Donovan;Erika Pearson;Drew Tietz;Elizabeth Do;Lauren Jansen;Chris Sparages;Michele McAuliffe;Tiffany Vo;Lauren Sohn;Elina Makino

HYPOTHESIS: sustained therapeutic effect could be achieved by administration of IDUA-secreting allogeneic human cells shielded within spheres designed to avoid immune rejection and pericapsular fibrotic overgrowth (PFO)

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