Aldevron, LLC products

A simple solution from R&D to clinical material. Aldevron provides research grade Cas9 nucleases for use in development work as well as standard GMP products for clinical studies. The concentration for these products is 10 mg/mL, dispensed in the following sizes: Research Grade: 0.25 mg and 5 mg vials. GMP: 10 mg and 50 mg vials.

Our in vitro transcription (IVT) enzymes are qualified both by activity assays and functionally for RNA synthesis and can be custom manufactured to meet your specific project requirements from milligram to multigram scale. View the table below for a summary of our IVT enzymes.

Aldevron provides pALD Lenti packaging plasmids through our partnership with OXGENE, who have optimized them for lentiviral vector production.  They are immediately available at all quality levels, eliminating the need to manufacture custom batches. This reduces your costs and significantly reduces time to manufacture vectors for clinical trials.

Find the Right Backbone for your Application. Aldevron, your trusted partner since 1998, has several cloning backbones available. These cloning backbones are empty vectors that can be modified to fit your needs. Each vector is available at research grade and is royalty and license free from research through commercial applications. pALD-CV42 and pALD-CV77 are ideal for researchers who do not have a cloning backbone available. This construct set is appropriate for a wide range of applications. Researchers have also used the pALD-CV77 backbone sequence successfully in clinical trials.

The gWiz plasmids are designed for the highest level of gene expression in a wide range of mammalian cells and tissues. They contain a proprietary modified promoter, followed by intron A from the CMV immediate early gene, and a high-efficiency artificial transcription terminator. gWiz expression vectors are constructed using a plasmid backbone that has been extensively modified to achieve enhanced levels of transgene expression in mammalian cells.