Applied BioPhysics, Inc.
Applied BioPhysics, Inc. applies the results of biophysical research to provide practical tools for cell research and drug discovery. Applied BioPhysics manufactures ECIS™ (Electric Cell-Substrate Impedance Sensing) instruments and arrays for monitoring the behavior of cells in tissue culture. We not only pride ourselves for being the founders of an automated, quantitative, real-time instrument, we also pride ourselves on being as academic minded as we are business savy. Our primary intention is to provide an instrument that answers the researchers experimental question(s). A system sitting idle is as much of a loss to you as it is to our company. Instruments are located throughout the United States as well as in Asia and Europe.
Company details
Find locations served, office locations
- Business Type:
- Manufacturer
- Industry Type:
- Medical Research
- Market Focus:
- Internationally (various countries)
About Us
ECIS™ or Electric Cell-substrate Impedance Sensing is an impedance based method to study many of the activities of animal cells when grown in tissue culture in real-time. These include morphological changes, cell locomotion, and other behaviors directed by the cell's cytoskeleton. ECIS™ technology was invented by Drs. Ivar Giaever and Charles R. Keese while working at General Electric Corporate Research and Development, but its commercial potential was not explored as it fell outside of GE's core interests. In 1991, as the applications of the technology became more apparent, Drs Giaever and Keese formed Applied BioPhysics, Inc. as a private company to develop, commercialize and market ECIS™ and other biophysical technologies. Applied BioPhysics is located next to the Rensselaer Polytechnic Institute campus, where several collaborative research projects are ongoing in the academic laboratories.
Since the formation of the company, the ECIS™ approach has been applied to numerous investigations including measurements of the invasive nature of cancer cells, the barrier function of endothelial cells, in vitro toxicity testing as an alternative to animal testing, and signal transduction involving GPCR's for modern drug discovery.
Instruments are located throughout the United States as well as in Asia and Europe. Customers include Johns Hopkins University, The University of Tokyo, Vanderbilt University, Brown University, Genentech, and Allergan to mention a few. Drs. Giaever and Keese continue to develop new innovations to enhance the ECIS technology including most recently an automated wound healing assay and a device to study the behavior of cells under flow conditions both of which are now commercially available.
Our Mission
Applied BioPhysics manufactures ECIS™ (Electric Cell-Substrate Impedance Sensing) instruments and arrays for monitoring the behavior of cells in tissue culture. We not only pride ourselves for being the founders of an automated, quantitative, real-time instrument, we also pride ourselves on being as academic minded as we are business savy. Our primary intention is to provide an instrument that answers the researchers experimental question(s). A system sitting idle is as much of a loss to you as it is to our company.
We thrive on creating a strong ECIS™ community, a network between ECIS™ users, and with Applied BioPhysics. We rely heavily on peer reviewed publications to learn about how ECIS is being used for various applications. In turn we are able to connect ECIS™ users with one another when questions arise about specific assays, cell lines, experimental conditions, and protocols.
We have a dedicated team of employees that make our customers and their research a priority. It is not uncommon for us to make ourselves available after hours when researchers have questions, or need assistance.
All of our products are manufactured in the USA, 95 percent of which are manufactured at our facility in Troy, NY.
Applied BioPhysics, Inc. has a mission to bring you innovative technology to benefit your research, with guaranteed satisfaction through manufacturing and person to person communication. Reliable, reproducible, and real-time results are our universal approach to the cell-science community.
Environmental Impact Statement
Applied BioPhysics is dedicated to minimizing its environmental impact, and ensuring a sustainable future by finding opportunities within both its operations and business practices to promote environmentally sound choices.
Applied BioPhysics is developing innovative solutions to bring about change by:
- Continuing improvement in daily operations that contribute to the health and well-being of its employees, as well as the surrounding community.
- Promoting the practices of reducing, reusing and recycling of all materials.
- Conducting its business activities in the most environmentally sound manner possible.
