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Cellomics Technology, LLC products
CRISPR-Cas9 - Lentiviral sgRNA CRISPR/Cas9 All-in-One
Cellomics - Lentiviral Cish
CISH (Cytokine Inducible SH2 Containing Protein) contains a SH2 domain and a SOCS box domain. SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. CISH may be a substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.