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Tissue Microarrays (TMA)
Provitro - Neoplastic (Tumour) Tissue Microarrays (TMA)
Neoplastic (tumour) TMA include various neoplasms which are precisely graded, typed and classified according to WHO and/or UICC criteria.
Provitro - Tissue Microarrays (TMA)
Normal TMA include normal tissue samples from a wide range of different human organs or matched organs from different species on one single slide.
Provitro - Inflammatory + Autoimmune Tissue Microarrays (TMA)
Cultures based on cell monolayers have the advantage of reducing tissue complexity to a minimum. However, the lack of normal physiological cell-matrix interactions leads the cell metabolism and gene expression towards a dedifferentiated state. Compared to a monolayer, three-dimensional cultures are associated with a higher cell density, and nutrient supply depends on diffusion through the extracellular matrix. This requires more exacting culture conditions which can be achieved using automated medium replacement in a perfusion culture system, thereby guaranteeing a stable concentration of nutrients, stable pH, and reduced risk of contamination.
Provitro - Customised Tissue Microarrays (TMA)
Customised TMA include service of tissue microarray manufacturing and slide cutting according to customer’s needs. Additional immunohistochemistry service is available on request.
Provitro - Cardiovascular Tissue Microarrays (TMA)
Cardiovascular TMA include samples from cardiovascular normal tissue and myocardial infarction, myocardial hypertrophy of left heart/right heart and vascular tissue samples including classification of artheriosclerosis according to Stary.