Vascular Articles
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Clinical Research On-Demand: How the University of Washington’s Theberge Lab is Using Tasso to Study Unpredictable Events in Real Time - Case Study
Many important research questions cannot be studied under controlled circumstances. Events like natural disasters or disease exposure often occur without warning and prevent in-person clinic visits, making timely observation difficult without a flexible approach. At the University of Washington, researchers are partnering with Tasso to study these scenarios by deploying on-demand remote ...
By Tasso, Inc.
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Bio-Ink: Printing the Future of Medicine and Beyond
Bio-ink is a revolutionary material that is rapidly changing the fields of medicine, tissue engineering, and even bioprinting food. This fascinating substance is essentially a type of ink made from living cells and other biocompatible materials that can be used to 3D print complex biological structures. What is Bio-Ink Made Of? The composition of bio-ink can vary depending on the desired ...
By Matexcel
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Cytokines: The Master Regulators of Immunity and Inflammation
Cytokines are a broad class of tiny proteins that are essential for controlling inflammation and immunological responses. Numerous cell types, including fibroblasts, endothelial cells, immunological cells, and epithelial cells, produce these signaling molecules. Serving as intermediaries, they synchronize various cell functions to elicit the body's defense mechanisms against infections, tissue ...
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The Role of Exosome RNA in Cancer
The Relationship Between Exosomes and Cancer Exosomes are nanoscale vesicles derived from intracellular lysosomes that shuttle a variety of biomolecules, such as nucleic acids, proteins, lipids, amino acids and metabolites, and play a key role in regulating intercellular communication. Exosomes can be secreted by almost all types of cells, including immune cells, blood cells, neuronal cells, ...
By CD Genomics
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Peptides for Osteoporosis Research
Introduction to OsteoporosisOsteoporosis is a systemic multi-causal skeletal disease that is prone to fractures due to changes in systemic bone mass and microstructure of bone tissue, resulting in increased bone fragility. Osteoporosis is a type of disease that is difficult to cure. According to the etiology, it can be divided into primary osteoporosis, secondary osteoporosis and idiopathic ...
By BOC Sciences
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Breakthrough Innovations in Bipolar Hip Prosthesis: Improving Mobility and Stability
Hip replacement surgery has been a life-changing procedure for individuals grappling with debilitating hip conditions like osteoarthritis, rheumatoid arthritis, or hip fractures. Over the years, continuous strides in medical technology have ushered in substantial enhancements in hip prostheses, offering patients the prospect of regaining mobility, alleviating pain, and improving their overall ...
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Cytokine Involvement in Inflammatory Immune Disorders
Cytokines, small molecules with potent biological activity, are primarily synthesized by immune and non-immune cells (e.g., vascular endothelial cells, epidermal cells, fibroblasts) in response to stimulation. These signaling molecules form intricate networks that contribute to immune responses, inflammatory reactions, cell proliferation, and growth. Cytokine Dysregulation in Systemic Immune ...
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Huateng Pharma Supplies Minoxidil Intermediate 2,4-Diamino-6-chloropyrimidine (CAS NO.156-83-2)
Minoxidil was first introduced by Upjohn Company of the United States, and was first used as an oral drug for the treatment of refractory hypertension in the 1970s. In later clinical applications, doctors observed hair regrowth and generalized excessive hair in balding patients, which led to the development of minoxidil preparations. Minoxidil can increase local blood supply, stimulate the ...
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CADM: A New Generation of Tumor Suppressor Genes
About Tumor Suppressor Genes A tumor suppressor gene, also known as anti-onco gene, is an essential component of the body's defense against cancer. It usually facilitates apoptosis. With its absence, the human body will be functioning without its “brake” of cell proliferation. Cells are potent to go under abnormal growth processes and finally lead to tumor/cancer. Here are some key ...
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Huateng Pharma Supplies Some Intermediates of CDK4/6 Inhibitors for Treatment of Advanced Breast Cancer
Breast cancer is the most frequent cancer among women, impacting 2.1 million women each year, and also causes the greatest number of cancer-related deaths among women. In 2018, it is estimated that 627,000 women died from breast cancer – that is approximately 15% of all cancer deaths among women. While breast cancer rates are higher among women in more developed regions, rates are ...
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The Tumor Marker: Vascular Endothelial Growth Factor 165 (VEGF165)
Tumors and Blood Vessel Growth Tumor, as an abnormal mass of cells, has blood vessels of various sizes that can be seen everywhere on the surface and deep within it. Nutrients for life are continuously supplied to the depths of tumor cells through these blood vessels. As the tumor continues to grow, nearby blood vessels also undergo rapid and chaotic growth, with these newly formed capillaries ...
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The tiny grabber that plucks blood clots out of a vein (The Mail on Sunday)
Thousands of patients suffering from deep vein thrombosis (DVT) are set to benefit from a lifesaving procedure using a new blood clot grabbing device pioneered by NHS specialists. The treatment involves inserting a stent, a tiny, ball- shaped wire cage into a blocked vein. Once in position, the collapsible cage is expanded and ‘ catches’ the clot. When the device is pulled out, the ...
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New DVT device completes first-in-human trial (Venous News)
The first-in-human case using the new deep vein thrombosis (DVT) device Vetex thrombectomy catheter (Vetex Medical) has recently been completed in a multicentre study. The device has the potential to reduce hospital stays and costs associated with DVT treatment, a press release announces. According to Vetex Medical, the Vetex thrombectomy catheter is the first device to combine rotational and ...
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The latest developments of Medis QFR
December 2022 edition Given the regular posts of peer-reviewed scientific publications on the Medis QFR®, it is clear that this angio-based solution for coronary physiology is extensively used in clinical research and practice. We would like to share these publications with you so that you remain up to date about the research that is ongoing worldwide with this innovative solution, ...
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Improving Clinical Practice Can Benefit Staff and Patients - Case Study
Background A 16 y/o male with a history of irritable bowel disease presents to the Emergency Department vomiting blood. He has an ostomy in place. His initial vital signs were BP 82/59, HR 160, SI 1.95. He was ill-appearing, with skin gray and ashen. The staff placed a 20-gauge peripheral IV and infused a 1-liter NS bolus using the LifeFlow PLUS and the QinFlow Warrior blood and fluid warmer. ...
By 410 Medical
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Alucent Biomedical Re-Envisioning PAD Treatment with a Natural Vascular Scaffold
Start-up Alucent Biomedical is using a light-activated molecule, delivered via a balloon catheter, to create a natural vascular scaffold in diseased peripheral vessels, with the aim of providing a long-lasting treatment option that maintains patency while leaving nothing behind in the vessel. Alucent Biomedical Inc. is rethinking peripheral artery disease (PAD) treatment with a novel natural ...
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Treatment for shoulder pain - Case Study
Treatment for shoulder pain Gabi Zeilig, MD, Dept of Neurological Rehabilitation The Chaim Sheba Medical Center, Tel Hashomer, Israel. Purpose of the study: to test the efficacy of the TerraQuant medical device on shoulder pain resulting from inflammation (OA, Tendonitis, Bursitis). Background: TerraQuant is a unique device which combines low level pulse laser therapy (LLLT), pulsating ...
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EluNIR First-in-Patient Implantation- Case Study
Background This paper outlines the first in-patient implantation of the EluNIR™ ridaforolimus eluting elastomeric stent (Medinol Ltd.). This complex case involved a patient with a flow-limiting lesion in a native coronary artery post bypass surgery. The new EluNIR stent system includes a stent with a low metal footprint which comprises struts of variable width: ultra-narrow struts having ...
By Medinol
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EluNIR DES in a Challenging Case - Case Study
Background: This paper describes a challenging case of implantation of the EluNIR™ Ridaforolimus eluting elastomeric stent (Medinol Ltd.). This complex case involved a patient with a flow-limiting lesion in a native coronary artery post bypass surgery. The new EluNIR stent system includes a stent with a low metal footprint that comprises struts of variable width: ultra-narrow struts ...
By Medinol
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Spatial profiling of chromatin accessibility in mouse and human tissues
Abstract Cellular function in tissue is dependent on the local environment, requiring new methods for spatial mapping of biomolecules and cells in the tissue context1. The emergence of spatial transcriptomics has enabled genome-scale gene expression mapping2,3,4,5, but the ability to capture spatial epigenetic information of tissue at the cellular level and genome scale is lacking. Here we ...
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