CytomX Therapeutics Announces Retirement of Frederick W. Gluck from Board of Directors

CytomX Therapeutics, Inc. (Nasdaq: CTMX), a leader in the field of conditionally activated oncology therapeutics, today announced that Frederick W. Gluck is retiring from its board of directors, effective June 30th, 2022.

“It has been an honor to serve on the CytomX board since the company’s founding,” said Frederick W. Gluck. “With a deep and differentiated clinical pipeline, a world class team and strong partnerships, CytomX is well positioned to deliver on its vision of bringing safer and more effective therapies to cancer patients and I wish the company continued success in the years to come.”

Mr. Gluck has served as a member of the CytomX Therapeutics board since the company’s founding in 2008. He was a co-founder of CytomX, LLC, the predecessor company, and served as its chairman of the board and chief executive officer from 2006 to 2008.

“As our co-founder, Fred’s wide ranging strategic acumen has been instrumental in shaping our corporate evolution, positioning CytomX as a leader in the field of conditional activation of cancer therapeutics,” said Sean McCarthy, D.Phil., chief executive officer and chairman of the board of directors. “We are grateful for Fred’s many valuable contributions to CytomX and the board throughout the years, and we wish him all the best in his retirement.”

Following Mr. Gluck’s retirement, CytomX’s board will consist of eight directors, seven of whom are considered as independent under NASDAQ rules.

About CytomX Therapeutics, Inc.
CytomX is a clinical-stage, oncology-focused biopharmaceutical company dedicated to destroying cancer differently. By pioneering a novel class of conditionally activated biologics, powered by its Probody® technology platform, CytomX’s goal is to transcend the limits of current cancer treatments by successfully leveraging therapeutic targets that were once thought to be inaccessible. CytomX’s robust and differentiated pipeline includes the wholly-owned praluzatamab ravtansine (CX-2009), an investigational conditionally activated antibody-drug conjugate (ADC) directed toward CD166, and CX-2029, an investigational conditionally activated ADC directed toward CD71 being developed in collaboration with AbbVie. These two programs are currently being evaluated in Phase 2 studies, targeting a variety of late-stage, difficult-to-treat cancer types, including breast cancer for praluzatamab ravtansine, and squamous non-small cell lung cancer, and head and neck squamous cell carcinoma for CX-2029. CytomX’s clinical pipeline also includes cancer immunotherapeutic candidates against validated targets such as the CTLA-4-targeting Probody therapeutics, BMS-986249 and BMS-986288, partnered with Bristol Myers Squibb, and our wholly-owned conditionally activated anti-PD-L1 antibody, pacmilimab (CX-072), as well as CX-904, a conditionally activated T-cell-engaging bispecific antibody targeting the epidermal growth factor receptor on tumor cells and the CD3 receptor on T cells, which is partnered with Amgen. In addition, CytomX has a diverse preclinical portfolio and strategic collaborations with multiple leaders in oncology, including AbbVie, Amgen, Astellas, and Bristol Myers Squibb. For more information about CytomX and how it is working to make conditionally activated treatments the new standard-of-care in the fight against cancer.