Drug Concentration Articles & Analysis
7 news found
Traditional methods of evaluating the efficacy of oral medications have often been limited by the inability to accurately measure the drug's concentration in the body. This has led to challenges in determining the optimal dosage and timing of administration, which can impact both the effectiveness and safety of the treatment. ...
Subjects were randomized into one of two sequences (a fasted state, and a fed state [after a high-fat test meal]) and dosed with a 25mg dose of CTx-1301 The primary PK endpoints were maximum concentration (expressed as Cmax) during the first 28 hours after dosing, and the total amount of the active pharmaceutical ingredient (API), dexmethylphenidate, in the blood (expressed as ...
“The RaniPill HC gives us the potential to deliver a much broader range of biologic drugs with its higher capacity of up to 20 mg of drug per capsule,” said Mir Imran, Rani’s Founder and Executive Chairman. ...
The new device is capable of delivering a drug payload of up to or more than 500% higher compared to the company’s current oral biologics capsule. ...
Unfortunately, these medications can have adverse effects if the drug level is too high. Conversely, if the drug level is too low, the patient’s condition may not be treated effectively. Current drug level methods are not rapid enough, which diminishes their clinical utility. ...
A Breakthrough Therapy designation provides more intensive FDA guidance on an efficient drug development program, an organizational commitment involving senior managers, and eligibility for rolling review and priority review. ...
Pegloprastide’s ratiometric readout attenuates common artifacts of fluorescent imaging, including differences in drug concentration and distance of the camera from the tissue area of interest. ...