Induced Inflammation Articles & Analysis
9 news found
Asthma remains a complex and multifactorial disease, with airway hyperresponsiveness to methacholine being a hallmark feature. A recent study by Rojas-Ruiz et al (2025) utilizes SCIREQ’s innovative physioLens (ex vivo) and flexiVent (in vivo) platforms to shed light on the interplay between lung tissue compliance and methacholine response, offering new insights into the mechanisms ...
Astaxanthin has gained popularity in recent years for its impressive health benefits, including its ability to reduce oxidative stress, inflammation, and UV-induced skin damage. As a natural compound derived from algae, astaxanthin is considered safe for consumption and is suitable for use in a wide range of products, from dietary supplements to skincare ...
Histological examinations and ultrasound analysis show that the use of this type of high-intensity currents (90mA) with frequencies in the 10-50Hz range, emitted in a randomized manner so as not to induce adaptation in the cells, act on the extracellular interstitium and on the remodelling and orientation of the reticular collagen fibres, thus improving skin tone and elasticity. ...
TNF’s primary role involves the regulation of immune cells, but it is also a pyrogen that induces fever and inflammation. In addition, TNF can inhibit viral replication and respond to sepsis by inducing Interleukins 1 and 6. It is one of the earliest cytokines produced and may have both a direct effect on cells and tissues and an indirect ...
Locus engineers bacteriophage – naturally occurring viruses that target bacteria – to: 1) kill pathogenic bacteria, while sparing good bacteria, through programmable, precision anti-bacterials with CRISPR-Cas3; and 2) utilize bacteria resident in the body to deliver therapeutic molecules to reduce inflammation or induce other biotherapeutic effects. ...
No Grade 4 or 5 esophagitis in patients treated with avasopasem Galera Therapeutics, Inc. (Nasdaq: GRTX), a clinical-stage biopharmaceutical company focused on developing and commercializing a pipeline of novel, proprietary therapeutics that have the potential to transform radiotherapy in cancer, today announced topline results from the six-week, Phase 2a, open-label, single-arm AESOP trial of ...
Locus engineers bacteriophage – naturally occurring viruses that target bacteria – to: 1) utilize bacteria resident in the body to deliver therapeutic molecules to reduce inflammation or induce other biotherapeutic effects; 2) kill pathogenic bacteria, while sparing good bacteria, through programmable, precision anti-bacterials with CRISPR-Cas3. ...
There was no evidence of clinically significant GT005-induced inflammation. Biomarker data from 13 patients, ranging from approximately seven months post treatment to nearly two years, continued to demonstrate sustained increases in vitreous complement factor I (CFI) levels compared to baseline in the majority of patients, as well as sustained decreases in ...
“Our investigational gene therapy, GT005, is designed to restore balance to an overactive complement system and reduce inflammation by increasing production of the CFI protein. We are excited by these early results from the FOCUS trial that showed GT005 has been well tolerated to date, increased CFI levels in a durable manner and caused down-regulation of an overactive ...