Size Reduction Articles & Analysis
10 news found
By manipulating key factors such as reservoir size, drug loading, and polymer selection, the team has achieved remarkable control over drug release rates. ...
“Benefits include a 30% reduction in size, reduced weight, improved reliability, lower EMI and simplified safety certification and compliance. ...
In a randomized, double-blind, placebo-controlled Phase 1b trial treating patients with chronic moderate to severe diabetic foot ulcer infection, topical pravibismane treatment plus standard of care demonstrated a numeric 85% wound size reduction versus 30% placebo plus standard of care. Pravibismane also demonstrated a numeric reduction in ...
Data from two recent studies (“PiCSO in ACS” and “OxAMI-PICSO”) showed that the use of the PiCSO Impulse System is associated with a significant infarct size reduction in anterior STEMI patients 1,2. Furthermore, OxAMI-PICSO3 showed an early improvement in coronary microvascular function post PiCSO treatment in both anterior and inferior ...
” A lot of factors can affect the solubility of candidate drug molecules, for example, molecular structure of solute, nature of solvent or co-solvents, crystal characteristics, particle size of the solid, complex formation, pH, common ion effect, effect of indifferent electrolytes on the solubility product, effect of electrolytes on the solubility of non-electrolytes, etc. ...
However, via its unique mechanism of action, the PiCSO Impulse System reduces the infarct size by intermittently occluding the coronary sinus outflow leading to improved microcirculatory function. Infarct size is strongly associated with reductions in heart failure hospitalizations and reduced mortality3 . The CE Mark file was supported by ...
However, via its unique mechanism of action, the PiCSO Impulse System reduces the infarct size by intermittently occluding the coronary sinus outflow leading to improved microcirculatory function. Infarct size is strongly associated with reductions in heart failure hospitalizations and reduced mortality3. The CE Mark study (PiCSO in ACS4 study), ...
Klaus Witte, M.D., cardiologist at Leeds Teaching Hospital NHS Trusts in the UK and a top enroller in the study, commented, “The Carillon System is the first mitral valve repair device to demonstrate a significant reduction in regurgitant volume and favorable LV remodeling, indicating a size reduction of the left ventricle. ...
Data from two recent studies (“PiCSO in ACS” and “OxAMI-PICSO”) showed that the use of the PiCSO Impulse System is associated with a significant infarct size reduction 1,2 . Furthermore, OxAMI-PICSO showed an early improvement of coronary microvascular function post PiCSO treatment. PiCSO therapy accelerates the microcirculatory recovery ...
PiCSO therapy accelerates the microcirculatory recovery resulting in significantly lower IMR (Index of Microcirculatory Resistance) at 24-48 hours when compared to controls leading to overall infarct size reduction. “These clinical results are very encouraging. ...