MedChemExpress - Model Tesnatilimab - 2242758-08-1
Tesnatilimab is a human IgG4 monoclonal antibody that acts on the immune activating receptor NKG2D and has potential immunomodulatory and anti-inflammatory activity. Tesnatilimab can be used in the study of inflammatory bowel disease (IBD)[1][2].MCE products for research use only. We do not sell to patients.
Tesnatilimab
MCE China:Tesnatilimab
Brand:MedChemExpress (MCE)
Cat. No.HY-P99389
CAS:2242758-08-1
Purity:99.80%
Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping:Shipping with dry ice.
Description:Tesnatilimab is a human IgG4 monoclonal antibody that acts on the immune activating receptor NKG2D and has potential immunomodulatory and anti-inflammatory activity. Tesnatilimab can be used in the study of inflammatory bowel disease (IBD).
Species:Human
Isotype:Human IgG4 kappa
Recommend Isotype Controls:Human IgG4 (S228P) kappa, Isotype Control
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References:
[1]. Kasper Vadstrup, et al. Anti-NKG2D mAb: A New Treatment for Crohn's Disease? Int J Mol Sci. 2017 Sep 16;18(9):1997. [Content Brief]
[2]. Wei L, et al. The role of NKG2D and its ligands in autoimmune diseases: new targets for immunotherapy[J]. International Journal of Molecular Sciences, 2023, 24(24): 17545. [Content Brief]
Brand introduction:
• MCE (MedChemExpress) has a global exclusive compound library of more than 200 kinds, and we are committed to providing the most comprehensive range of high-quality small molecule active compounds for scientific research customers around the world;
• More than 50,000 highly selective inhibitors and agonists are involved in various popular signaling pathways and disease areas;
• The products cover a variety of recombinant proteins, peptides, commonly used kits, more PROTAC, ADC and other characteristic products, widely used in new drug research and development, life science and other scientific research projects;
• Provide virtual screening, ion channel screening, metabolomics analysis detection analysis, drug screening and other professional technical services;
• It has a professional experimental center and strict quality control and verification system;
• Provide LC/MS, NMR, HPLC, chiral analysis, elemental analysis and other quality inspection reports to ensure the high purity and high quality of products;
• The biological activity of the products has been verified by the experiments of customers in various countries;
• A variety of top journals such as Nature, Cell, Science and pharmaceutical patents have included the scientific research results of MCE customers;
• Our professional team tracks the latest pharmaceutical and life science research and provides you with the latest active compounds in the world;
• It has established long-term cooperation with the world's major pharmaceutical companies and well-known scientific research institutions。