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MedChemExpressModel 3-Aminobenzoic acid - 99-05-8

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3-Aminobenzoic acid (3-ABA) is an orally active anti-inflammatory agent targeting the tight junction (TJ) regulatory pathways in intestinal epithelial cells. 3-Aminobenzoic acid improves intestinal inflammation by enhancing intestinal barrier integrity and reducing epithelial permeability. It can be used in studies related to improving gut health. Additionally, 3-Aminobenzoic acid analogs can act as γ-aminobutyric acid transaminase (GABA-AT) inhibitors, exhibiting anticonvulsant effects[1][2][3][4].
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3-Aminobenzoic acid

MCE China:3-Aminobenzoic acid

Brand:MedChemExpress (MCE)

Cat. No.HY-I0746

CAS:99-05-8

Synonyms:m-Aminobenzoic acid; 3ABA

Purity:99.93%

Storage:Store at room temperature 3 years In solvent -80°C 2 years -20°C 1 year

Shipping:Room temperature in continental US; may vary elsewhere.

Description:3-Aminobenzoic acid (3-ABA) is an orally active anti-inflammatory agent targeting the tight junction (TJ) regulatory pathways in intestinal epithelial cells. 3-Aminobenzoic acid improves intestinal inflammation by enhancing intestinal barrier integrity and reducing epithelial permeability. It can be used in studies related to improving gut health. Additionally, 3-Aminobenzoic acid analogs can act as γ-aminobutyric acid transaminase (GABA-AT) inhibitors, exhibiting anticonvulsant effects.

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References:

[1]. Tanaka M, et al. Exploring 3-Aminobenzoic Acid as a Therapeutic Dietary Component for Enhancing Intestinal Barrier Integrity in Ulcerative Colitis[J]. bioRxiv, 2024: 2024.08. 18.608525.

[2]. Tanaka M, et al. P095 Accelerated degradation of gut barrier-protecting 3-aminobenzoic acid exacerbate colitis in Inflammatory Bowel Disease[J]. Journal of Crohn's and Colitis, 2024, 18(Supplement_1): i374-i374.

[3]. Kumar A, et al. 3-Aminobenzoic Acid Analogues as a Novel GABA-at Inhibitors: Synthesis, Pharmacological Evaluation and Molecular Docking Studies[J]. Drug Discovery and Development, 2014, 1(2): 110-120.

Brand introduction:
•   MCE (MedChemExpress) has a global exclusive compound library of more than 200 kinds, and we are committed to providing the most comprehensive range of high-quality small molecule active compounds for scientific research customers around the world;
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•   Provide virtual screening, ion channel screening, metabolomics analysis detection analysis, drug screening and other professional technical services;
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•   The biological activity of the products has been verified by the experiments of customers in various countries;
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•   Our professional team tracks the latest pharmaceutical and life science research and provides you with the latest active compounds in the world;
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