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antibody drug conjugates adc

Antibody-Drug Conjugates (ADC)

FromSword Diagnostics, Inc.

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Sword scientists will use our cell-based assay development expertise to develop a customized method to corroborate the binding specificity of your antibody-drug conjugate (ADC). Our understanding of the molecular basis of cellular growth, proliferation, and differentiation is continually evolving as the genes, proteins, and biochemical pathways critical to these important cellular processes are investigated and understood.

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In oncology, that understanding has led to the development of new immunotherapeutic approaches to treating cancer. One such approach, the ADC, involves the generation of an antibody conjugated to a “payload,” usually a toxin, drug, or radionuclide. The antibody provides the binding specificity and serves to target the toxic payload of the ADC to malignant cells that express the antibody’s ligand on the cell surface.

Based on your specifications, our scientists will develop a bioanalytical method that will demonstrate the binding of your ADC to the cellular target of interest. The bioanalytical method will be performance qualified as fit for the assay’s purpose, whether the ADC is in early stage research and development or later stage preclinical.