Boston -Model BOS-342 -Bispecific Antibody
BOS-342 is a bispecific antibody comprised of an anti-GPC3 antagonistic antibody linked to a 4-1BB (CD137) agonistic anticalin protein.
Most popular related searches
cancer cell
tumor infiltration
tumor infiltrating
immune cell
solid tumor
tumor immunity
tumor immune
oncology
- BOS-342 binds with high affinity to cells expressing human GPC3 and 4-1BB.
- It is designed to accumulate in GPC3 positive tumor cells where it will activate 4-1BB on the tumor infiltrating immune cells.
- BOS-342 has the potential to be active in HCC and other solid tumors expressing GCP3.