Vala -Model Cat. CXPR-25 -hiPSC-Derived Microglia Cell

Background: Microglia are central nervous system innate immune support cells that function remarkably like peripheral macrophages [1]. Microglia continually monitor neuronal function through direct cell-cell contacts and exert neuroprotective effects in response to stress [2]. By maintaining brain homeostasis, clearing cellular debris [3], pruning synapses [4], and eliminating protein aggregates [5], microglia play key roles in neurodevelopment [6], Alzheimer’s Disease [7], Parkinson’s Disease [8], ALS [9], traumatic brain injury [10], and many other central nervous system conditions