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  4. SkinEthic - Model RHE - Human Epidermis

SkinEthicModel RHE - Human Epidermis

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SkinEthic RHE is an in vitro reconstructed human epidermis from normal human keratinocytes cultured on an inert polycarbonate filter at the air-liquid interface, in a chemically defined medium. This model exists at different stages of maturity. This model is histologically similar to in vivo human epidermis.

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Specific markers

Differentiation markers:

Dermal-Epidermal junction markers

  • Type IV collagen
  • Laminin V (See picture)
  • Alpha6Beta4-integrin
  • BP antigen

Proliferation markers

  • Ki67